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Drug-Target Interaction

Drug

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PubChem ID:74990
Structure:
Synonyms:
(1,4'-Bipiperidine)-1'-carboxylic acid, (4S)-4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano(3',4':6,7)indolizino(1,2-b)quinolin-9-yl ester, monohydrochloride
(1,4'-Bipiperidine)-1'-carboxylic acid, 3,4,12,14-tetrahydro-4,11-diethyl-4-hydroxy-3,4-dioxo-1H-pyrano(3',4':6,7)indolizino(1,2-b)quinolin-9-yl ester, monohydrochloride, (S)-
(4s)-4,11-diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1h-pyrano[3',4
100286-90-6
111348-33-5
7-Ethyl-10-(4-(1-piperidino)-1-piperidino)carbonyloxy camptothecin hydrochloride
Ambap2597
C11294
Campto
Camptosar
Camptothecin 11
Camptothecin 11 hydrochloride
Camptothecin analog
CPT 11
CPT-11
DQ-2805
Irinotecan
Irinotecan HCl
Irinotecan hydrochloride
LS-44591
NCGC00095190-01
NCGC00095190-02
NSC-616348
NSC616348
SPECTRUM1505821
TL8000040
Topotecin
U 101440E
U-101440E
[1,4'-Bipiperidine]-1'-carboxylic acid, 4,11-diethyl-3,4,12, 14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7] indolizino[1,2-b]quinolin-9-yl ester, monohydrochloride (S)-
ATC-Codes:

Target

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Uniprot ID:Q6GRK0_HUMAN
Synonyms:
cDNA, FLJ93427, Homo sapiens cytochrome P450, family 3, subfamily A, polypeptide 4(CYP3A4), transcript variant 1, mRNA
Cytochrome P450 family 3 subfamily A polypeptide 4
Cytochrome P450, family 3, subfamily A, polypeptide 4
Cytochrome P450, family 3, subfamily A, polypeptide 4, isoform CRA_a
Cytochrome P450, subfamily IIIA, polypeptide 4
EC-Numbers:-
Organism:Homo sapiens
Human
PDB IDs:-

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: