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Drug-Target Interaction

Drug

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PubChem ID:667490
Structure:
Synonyms:
1,7-Dihydro-6H-purine-6-thione
1,9-dihydro-6H-purine-6-thione
1H-Purine, 6-mercapto-
3,7-dihydropurine-6-thione
39454-94-9
3H-Purine-6-thiol
50-44-2
5759-99-9
5818-33-7
5818-60-0
6 Mercaptopurine
6 Mercaptopurine Monohydrate
6 MP
6 Thiohypoxanthine
6 Thiopurine
6-Mercaptopurin
6-Mercaptopurine
6-Mercaptopurine monohydrate
6-Merkaptopurin
6-Merkaptopurin [Czech]
6-MP
6-Purinethiol
6-Thiohypoxanthine
6-Thiopurine
6-Thioxopurine
6112-76-1
6112-76-1 (monohydrate)
63810_FLUKA
6H-Purine-6-thione, 1,7-dihydro-
6H-Purine-6-thione, 1,7-dihydro- (9CI)
6MP
7-Mercapto-1,3,4,6-tetrazaindene
7H-purine-6-thiol
9H-Purin-6-yl hydrosulfide
9H-Purine-6(1H)-thione
AC-11464
AC1LDI73
AG-670/31547064
AIDS-007317
AIDS007317
AKOS000170222
AKOS000275858
AKOS005224624
Ambap50-44-2
Ambap5371
BB_SC-0064
BSPBio_001981
BW 57 323H
BW 57-323H
BW 57323H
C01756
C02380
C5H4N4S
CCG-35344
CCG-39915
CCRIS 2761
CHEBI:2208
CHEBI:50667
CHEMBL1425
cMAP_000033
CPD000544948
D015122
D04931
DB01033
DivK1c_000493
EINECS 200-037-4
F3329-0452
FT-0083571
Glaxo Wellcome Brand of 6 Mercaptopurine
Glaxo Wellcome Brand of 6-Mercaptopurine
GlaxoSmithKline Brand of 6 Mercaptopurine
GlaxoSmithKline Brand of 6-Mercaptopurine
HMS1920L07
HMS2091B20
HMS2236L06
HMS3259N03
HMS501I15
HSDB 3235
Hypoxanthine, thio-
I14-1716
IDI1_000493
Ismipur
KBio1_000493
KBio2_001401
KBio2_002363
KBio2_003969
KBio2_004931
KBio2_006537
KBio2_007499
KBio3_001481
KBio3_002842
KBioGR_001493
KBioGR_002363
KBioSS_001401
KBioSS_002366
Leukeran
Leukerin
Leukerin, 99% - Carc
Leupu rin
Leupurin
LS-141
M0063
Mercaleukim
Mercaleukin
Mercaptopurin
Mercaptopurin [German]
Mercaptopurina
Mercaptopurina Wellcome
Mercaptopurina [INN-Spanish]
Mercaptopurine
Mercaptopurine (anhydrous)
Mercaptopurine (INN)
Mercaptopurine (VAN)
Mercaptopurine anhydrous
Mercaptopurine Monohydrate
Mercaptopurine, 6-
Mercaptopurine-Supplied by Selleck Chemicals
Mercaptopurinum
Mercaptopurinum [INN-Latin]
Mercapurin
Merkaptopuryna
Merkaptopuryna [Polish]
Mern
MLS001066623
MLS001304020
MLS001304953
MolPort-001-783-696
MolPort-003-846-751
MP
NCGC00091641-02
NCGC00091641-03
NCGC00091641-04
NCGC00094717-01
NCGC00094717-02
NCGC00094717-03
NCGC00188973-01
NCI-C04886
NCI60_041653
NCIMech_000025
NINDS_000493
NSC 755
NSC-755
NSC755
PB314676292
PM6
Puri Nethol
Puri-Nethol
Purimethol
purine antimetabolite: inhibits nucleic acid replication
Purine, 6-mercapto-
Purine-6(1H)-thione
Purine-6-thiol
Purine-6-thiol, monohydrate
Purine-6-thione
Purinethiol
Purinethol
Purinethol (TN)
Purinethol, 6-mercaptopurine, 6-MP, Mercaptopurine
S1305_Selleck
SAM002589937
SMR000544948
SPBio_000219
SPECTRUM1500387
Spectrum2_000060
Spectrum3_000491
Spectrum4_000857
Spectrum5_000950
Spectrum_000921
ST086505
ST086506
ST5298927
STK727062
Thiopurine
U-4748
UNII-PKK6MUZ20G
Wellcome Brand of 6 Mercaptopurine
Wellcome Brand of 6-Mercaptopurine
WLN: T56 BM DN FN HNJ ISH
ZINC04658290
ATC-Codes:
Side-Effects:
Side-EffectFrequency
myelodysplastic syndrome0
vomiting0
oral moniliasis0
polyps0
cyst0
inflammatory bowel disease0
nausea0
anorexia0
intestinal ulcer0
diarrhea0
sepsis0
alopecia0
hyperpigmentation0
fever0
pancreatitis0
thrombocytopenia0
hyperuricemia0
anemia0
sprue0
leukopenia0

Target

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Uniprot ID:IMDH2_HUMAN
Synonyms:
IMP dehydrogenase 2
IMPD 2
IMPDH-II
Inosine-5'-monophosphate dehydrogenase 2
EC-Numbers:1.1.1.205
Organism:Homo sapiens
Human
PDB IDs:1B3O 1NF7 1NFB
Structure:
1NFB

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: