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Drug-Target Interaction

Drug

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PubChem ID:439155
Structure:
Synonyms:
(S)-5'-(S)-(3-Amino-3-carboxypropyl)-5'-thioadenosine
1aqi
1jqd
1nw7
1qan
1s4d
2-S-adenosyl-L-homocysteine
2bqz
2h23
5'-Deoxy-S-adenosyl-L-homocysteine
75899-14-8
979-92-0
A9384_SIGMA
Adenosine, 5'-S-(3-amino-3-carboxypropyl)-5'-thio-, L- (8CI)
adenosine, 5'-S-[(3S)-3-amino-3-carboxypropyl]-5'-thio-
adenosyl-homo-cys
Adenosyl-L-homocysteine
adenosylhomo-cys
Adenosylhomocysteine
AdoHcy
BRN 5166233
C00021
CHEBI:16680
D-Ribitol,
D-Ribitol, 5-S-(3-amino-3-carboxypropyl)-1-C-(7-amino-1H-pyrazolo(4,3-d)pyrimidin-3-yl)-1,4-anhydro-5-thio-, (1S,5(S))-
Formycinylhomocysteine
Homocysteine, S-adenosyl-, L- (6CI,7CI)
L-Homocysteine, S-(5'-deoxyadenosin-5'-yl)-
L-Homocysteine, S-(5'-deoxyadenosin-5'-yl)- (9CI)
L-S-Adenosylhomocysteine
LS-143740
nchembio.153-comp1
S-(5'-adenosyl)-L-homocysteine
S-(5'-deoxyadenosin-5'-yl)-L-homocysteine
S-(5'-Deoxyadenosine-5')-L-homocysteine
S-adenosyl-homocysteine
S-Adenosyl-L-homocysteine
S-Adenosylhomocysteine
S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-ribofuranos-5-yl]-L-homocysteine
SAH
ST5298941

Target

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Uniprot ID:DPHB_PYRHO
Synonyms:
Diphthamide biosynthesis methyltransferase
Probable diphthine synthase
EC-Numbers:2.1.1.98
Organism:Pyrococcus horikoshii
PDB IDs:1VCE 1WNG 2DEK 2DSG 2DSH 2DSI 2DV3 2DV4 2DV5 2DV7 2DXV 2DXW 2DXX 2E07 2E08 2E15 2E16 2E17 2E4N 2E4R 2E7R 2E8H 2E8Q 2E8R 2E8S 2ED3 2ED5 2EEQ 2EGB 2EGL 2EGS 2EH2 2EH4 2EH5 2EHC 2EHL 2EJJ 2EJK 2EJZ 2EK2 2EK3 2EK4 2EK7 2EKA 2EL0 2EL1 2EL2 2EL3 2ELD 2ELE 2EMR 2EMU 2EN5 2ENI 2HR8 2HUQ 2HUT 2HUV 2HUX 2OWF 2OWG 2OWK 2OWU 2OWV 2P2X 2P5C 2P5F 2P6D 2P6I 2P6K 2P6L 2P9D 2PB4 2PB5 2PB6 2PCA 2PCG 2PCH 2PCI 2PCK 2PCM 2Z6R
Structure:
2Z6R

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
----

References: