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Drug-Target Interaction

Drug

show drug details
PubChem ID:2761171
Structure:
Synonyms:
.alpha.-Ethyl-thioisonicotinamide
.alpha.-Ethylisonicotinic acid thioamide
.alpha.-Ethylisonicotinoylthioamide
.alpha.-Ethylisothionicotinamide
.alpha.-Ethylthioisonicotinamide
1314 TH
1314 TN
1314-Th
1314TH
2-e thylisothionicotinamide
2-ethyl-4-aminothiocarbonylpyridine
2-Ethyl-4-pyridinecarbothioamide
2-Ethyl-4-thioamidylpyridine
2-Ethyl-4-thiocarbamoylpyridine
2-Ethyl-thioisonicotinamide
2-Ethylisonicotinic acid thioamide
2-ethylisonicotinic acid thiomide
2-Ethylisonicotinic thioamide
2-Ethylisonicotinothioamide
2-Ethylisonicotinoylthioamide
2-Ethylisothionicotinamide
2-ethylpyridine-4-carbothioamide
2-Ethylthioisonicotinamide
2-ethylthioisonicotinamide, Trecator SC, Amidazine, Ethionamide
3-Ethylisothionicotinamide
4-Pyridinecarbothioamide, 2-ethyl-
5-22-02-00360 (Beilstein Handbook Reference)
5261-38-1
536-33-4
:ethionamide
AB00051990
AC-13715
AC1MC4CB
AEOCXXJPGCBFJA-UHFFFAOYSA-
Aethionamidum
Aetina
Aetiva
AIDS-007656
AIDS-032283
AIDS007656
AIDS032283
alpha-Ethylisonicotinic acid thioamide
alpha-Ethylisonicotinoylthioamide
alpha-Ethylisothionicotinamide
alpha-ethylt hioisonicotinamide
alpha-Ethylthioisonicotinamide
Amidazin
Amidazine
Atina
Bayer 5312
Bayer5312
BPBio1_000563
BRD-K33710385-001-05-4
BRN 0116474
BSPBio_000511
BSPBio_002016
C07665
C8H10N2S
CAS-536-33-4
CCG-40212
CCRIS 287
CHEBI:4885
CHEMBL1441
CPD001370750
D005000
D00591
DB00609
DivK1c_000145
DRG-0196
E0695
E6005_SIGMA
EINECS 208-628-9
ET
ETH
Ethatyl
Ethimide
Ethina
Ethina (VAN)
Ethinamide
Ethionamid prothionamid
Ethionamide
Ethionamide & CRL8131
Ethionamide (JP15/USP/INN)
Ethionamide (JP16/USP/INN)
Ethionamide [USAN:BAN:INN:JAN]
Ethionamide [USAN:INN:BAN:JAN]
Ethionamide-Supplied by Selleck Chemicals
Ethionamidum
Ethionamidum [INN-Latin]
Ethioniamide
Ethylisothiamide
Ethyonomide
Etimid
Etimid (VAN)
Etiocidan
Etionamid
Etionamida
Etionamida [INN-Spanish]
Etionamide
Etionamide [DCIT]
Etioniamid
Etionid
Etionizin
Etionizina
Etionizine
ETP
F.I. 58-30
Fatoliamid
HMS1569J13
HMS1920M22
HMS2091F03
HMS2096J13
HMS2231F10
HMS2233J11
HMS3259K17
HMS500H07
HSDB 7473
IDI1_000145
Iridocin
Iridocin Bayer
Iridozin
Isonicotinamide, 2-ethylthio-
Isonicotinimidic acid, 2-ethylthio-
Isothin
Isotiamida
Itiocide
KBio1_000145
KBio2_001562
KBio2_004130
KBio2_006698
KBio3_001236
KBioGR_001213
KBioSS_001562
LS-199
MLS000069764
MLS001074114
MLS002454402
NCGC00016497-01
NCGC00016497-02
NCGC00016497-03
NCGC00016497-04
NCGC00016497-05
NCGC00016497-06
NCGC00091074-01
NCGC00091074-02
NCGC00091074-03
NCGC00091074-04
NCI-C01694
Nicotion
NINDS_000145
Nisotin
Nizotin
NSC 255115
NSC255115
Prestwick0_000526
Prestwick1_000526
Prestwick2_000526
Prestwick3_000526
Prestwick_842
Rigenicid
S1777_Selleck
SAM002554899
SBB055548
Sertinon
SMR000058716
SMR001370750
SPBio_001087
SPBio_002432
SPECTRUM1500292
Spectrum2_000994
Spectrum3_000428
Spectrum4_000547
Spectrum5_000979
Spectrum_001082
Teberus
TH 1314
Thianid
Thianide
Thioamide
Thiomid
Thioniden
Tianid
Tio-Mid
Tiomid
Trecator
Trecator SC
Trecator-SC
Trecator-SC (TN)
Trekator
Trescatyl
Trescazide
Tubenamide
Tubermin
Tuberoid
Tuberoson
UNII-OAY8ORS3CQ
WLN: T6NJ B2 DYZUS
Wyeth Brand of Ethionamide
ZINC03872520
ATC-Codes:
Side-Effects:
Side-EffectFrequency
abdominal pain0
impotence0
jaundice0
nausea0
neuritis0
optic neuritis0
purpura0
increased salivation0
stomatitis0
thrombocytopenia0
vomiting0
weight loss0
agitation0
blurred vision0
photosensitivity0
hypothyroidism0
postural hypotension0
anorexia0
mental depression0
diabetes mellitus0
diarrhea0
diplopia0
dizziness0
somnolence0
rash0
gynecomastia0
headache0
hepatitis0
hypersensitivity0
hypoglycemia0
hypotension0
acne0

Target

show target details
Uniprot ID:INHA_MYCTU
Synonyms:
Enoyl-[acyl-carrier-protein] reductase [NADH]
NADH-dependent enoyl-ACP reductase
EC-Numbers:1.3.1.9
Organism:Mycobacterium tuberculosis
PDB IDs:1BVR 1ENY 1ENZ 1P44 1P45 1ZID 2AQ8 2AQH 2AQI 2AQK 2B35 2B36 2B37 2H7I 2H7L 2H7M 2H7N 2H7P 2H9I 2IDZ 2IE0 2IEB 2IED 2NSD 2NTJ 2NV6 2PR2 3FNE 3FNF 3FNG 3FNH
Structure:
3FNH

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: