Drug Details

Name:

Tiludronate

PubChem ID:

60937

Pathway:

Show KEGG pathways

InChI:

InChI=1/C7H9ClO6P2S/c8-5-1-3-6(4-2-5)17-7(15(9,10)11)16(12,13)14/h1-4,7H,(H2,9,10,11)(H2,12,13,14)/f/h9-10,12-13H

SMILES:

c1cc(ccc1Cl)SC(P(O)(O)=O)P(O)(O)=O

Properties:

Formula:	C7H9ClO6P2S	Atoms:	17
Molecular Weight:	318.608	Rotatable Bonds:	4
H-bond Acceptors:	6	H-bond Donors:	0
logP:	2.0711

Targets:

Name	Uniprot ID	Source	References	Interaction
Mitogen-activated protein kinase 1	MK01_MOUSE	PROMISCUOUS	PMID 15922088	shows
Mitogen-activated protein kinase 3	MK03_MOUSE	PROMISCUOUS	PMID 15922088	shows
Protein kinase c	B8LXH5_TALSN	PROMISCUOUS	PMID 15922088	shows
Protein kinase C	KPC1_LYTPI	PROMISCUOUS	PMID 15922088	shows
Protein kinase C	KPC3_DROME	PROMISCUOUS	PMID 15922088	shows
RAF proto-oncogene serine/threonine-protein kinase	RAF1_MOUSE	PROMISCUOUS	PMID 15922088	shows
Tyrosine-protein phosphatase non-receptor type 1	PTN1_HUMAN	DrugBank	-	shows

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Synonyms:

(((p-Chlorophenyl)thio)methylene)diphosphonic acid

149845-07-8

149845-07-8 (disodium)

89987-06-4

96538-83-9

AC1L1U70

AC1Q3OOE

Acide tiludronique

Acide tiludronique [INN-French]

Acido tiludronico

Acido tiludronico [INN-Spanish]

Acidum tiludronicum

Acidum tiludronicum [INN-Latin]

acpmd

BIDD:GT0814

C08141

CHEMBL1350

D08599

DB01133

LS-183988

SR 41319

SR-41319

Tiludronate

Tiludronate disodium

Tiludronic acid

Tiludronic acid (INN)

Tiludronic Acid Disodium Salt

Tiludronic acid [BAN:INN]

Tiludronic acid [INN:BAN]

UNII-6PNS59HP4Y

[(4-chlorophenyl)sulfanyl-phosphonomethyl]phosphonic acid

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ATC-Codes:

M05BA05

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Side-Effects:

Side-Effect	Frequency
headache	0
nausea	0
tooth disorder	0
hyperparathyroidism	0
pain	0
peripheral edema	0
vomiting	0
bronchitis	0
diarrhea	0
vertigo	0
chest pain	0
anxiety	0
syncope	0
flushing	0
infection	0
somnolence	0
paresthesia	0
upper respiratory tract infection	0
anorexia	0
arthralgia	0
cataract	0
arthrosis	0
conjunctivitis	0
dyspepsia	0
insomnia	0
increased sweating	0
flatulence	0
cough	0
vitamin d deficiency	0
sinusitis	0
rhinitis	0
constipation	0
back pain	0
pathological fracture	0
rash	0
hypertension	0
nervousness	0
urinary tract infection	0
glaucoma	0
fatigue	0
pharyngitis	0
dry mouth	0
abdominal pain	0
asthenia	0
influenza	0
pruritus	0
dizziness	0
edema	0
gastritis	0

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