Drug Details

Name:

4-HYDROXY-3-[2-OXO-3-(THIENO[3,2-B]PYRIDINE-2-SULFONYLAMINO)-PYRROLIDIN-1-YLMETHYL]-BENZAMIDINE

PubChem ID:

5326514

Pathway:

Show KEGG pathways

InChI:

InChI=1/C19H19N5O4S2/c20-18(21)11-3-4-15(25)12(8-11)10-24-7-5-13(19(24)26)23-30(27,28)17-9-14-16(29-17)2-1-6-22-14/h1-4,6,8-9,13,23H,5,7,10,20-21H2/t13-/m0/s1

SMILES:

c1cc2c(cc(s2)S(N[C@H]2(CCN(CC3=CC(C=CC3=O)=C(N)N)C2=O))(=O)=O)nc1

Properties:

Formula:	C19H19N5O4S2	Atoms:	31
Molecular Weight:	445.515	Rotatable Bonds:	5
H-bond Acceptors:	8	H-bond Donors:	0
logP:	3.18

Targets:

Name	Uniprot ID	Source	References	Interaction
Cationic trypsin	TRY1_BOVIN	BindingDB	-	shows
Coagulation factor X	FA10_HUMAN	BindingDB	-	shows
Plasminogen	PLMN_HUMAN	BindingDB	-	shows
Prothrombin	THRB_HUMAN	BindingDB	-	shows
Tissue-type plasminogen activator	TPA_HUMAN	BindingDB	-	shows
Trypsin-1	TRY1_HUMAN	BindingDB	-	shows
Vitamin K-dependent protein C	PROC_HUMAN	BindingDB	-	shows

enlarge table

Synonyms:

1f0t

4-HYDROXY-3-[2-OXO-3-(THIENO[3,2-B]PYRIDINE-2-SULFONYLAMINO)-PYRROLIDIN-1-

4-HYDROXY-3-[2-OXO-3-(THIENO[3,2-B]PYRIDINE-2-SULFONYLAMINO)-PYRROLIDIN-1-YLMETHYL]-BENZAMIDINE

AC1NS0N1

CHEBI:45115

CHEMBL330572

CID5326514

DB02744

PR1

RPR131247

enlarge table