Drug Details

Name:

Src family kinase inhibitor PP2

PubChem ID:

4878

Pathway:

Show KEGG pathways

InChI:

InChI=1/C15H16ClN5/c1-15(2,3)21-14-11(13(17)18-8-19-14)12(20-21)9-4-6-10(16)7-5-9/h4-8H,1-3H3,(H2,17,18,19)/f/h17H2

SMILES:

CC(C)(C)n1c2c(c(c3ccc(cc3)Cl)n1)c(N)ncn2

Properties:

Formula:	C15H16ClN5	Atoms:	21
Molecular Weight:	301.774	Rotatable Bonds:	2
H-bond Acceptors:	4	H-bond Donors:	0
logP:	4.0651

Targets:

Name	Uniprot ID	Source	References	Interaction
Caspase	ICE_DROME	PROMISCUOUS	PMID 15073106	shows
Focal adhesion kinase 1	FAK1_MOUSE	PROMISCUOUS	PMID 15681821	shows
Protein kinase c	B8LXH5_TALSN	PROMISCUOUS	PMID 15102829	shows
Protein kinase C	KPC1_LYTPI	PROMISCUOUS	PMID 15102829	shows
Protein kinase C	KPC3_DROME	PROMISCUOUS	PMID 15102829	shows
Protein-tyrosine kinase IIB, 38K	Q7M0B5_RAT	PROMISCUOUS	PMID 10890901	shows
Proto-oncogene tyrosine-protein kinase LCK	LCK_HUMAN	BindingDB	-	shows
Proto-oncogene tyrosine-protein kinase Src	SRC_HUMAN	BindingDB	-	shows
Urokinase plasminogen activator receptor	Q6GY32_HUMAN	PROMISCUOUS	PMID 16407820	shows

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Synonyms:

"insolution™ pp2"

1-(tert-butyl)-3-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

1-tert-butyl-3-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

1-tert-butyl-3-(4-chlorophenyl)pyrazolo[3,4-d]pyrimidin-4-amine

11L-313S

172889-27-9

1H-pyrazolo[3,4-d]pyrimidin-4-amine,

1H-pyrazolo[3,4-d]pyrimidin-4-amine, 3-(4-chlorophenyl)-1-(1,1-dimethylethyl)-

1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 3-(4-chlorophenyl)-1-(1,1-dimethylethyl)- (9CI)

1qpe

4-amino-5-(4-chlorophenyl)-7-(t-butyl)pyrazolo(3,4-d)pyrimidine

4-Amino-5-(4-chlorophenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine

9-(4-chlorophenyl)-7-tert-butyl-3,5,8-triaza-7-azoniabicyclo[4.3.0]nona-2,4,6,9-tetraen-2-amine

AC1L1J5T

AC1Q3SH9

AG 1879

AG-1879

AG1879

AGL 1879

AKOS005078101

AR-1C5647

Bio2_000399

Bio2_000879

BiomolKI2_000058

BiomolKI_000052

BMK1-F4

BRD-K95785537-001-03-3

BRD-K95785537-001-04-1

BRD-K95785537-001-10-8

BSPBio_001118

C412373

CCG-100656

CHEBI:160597

CHEMBL406845

EC-000.2432

HMS1362H19

HMS1792H19

HMS1990H19

HMS2182N11

IDI1_002154

IN1144

InSolution&trade

InSolution™ PP2

K00048

KBio2_000458

KBio2_003026

KBio2_005594

KBio3_000855

KBio3_000856

KBioGR_000458

KBioSS_000458

Kinome_2000

ksc-8-108

KUC104577N

MLS000326622

MolPort-002-854-321

NCGC00163385-01

NCGC00163385-02

NCGC00163385-03

NCGC00163385-04

Oprea1_738267

PP 2

PP 2 (enzyme inhibitor)

pp2

PP2 cpd

PP2-AG1879

QTL1_000068

SMR000179218

Src family kinase inhibitor PP2

VU0205247-1

ZINC01383151

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