Drug Details

Name:

Darifenacin

PubChem ID:

444031

Pathway:

Show KEGG pathways

InChI:

InChI=1/C28H30N2O2/c29-27(31)28(23-7-3-1-4-8-23,24-9-5-2-6-10-24)25-14-17-30(20-25)16-13-21-11-12-26-22(19-21)15-18-32-26/h1-12,19,25H,13-18,20H2,(H2,29,31)/t25-/m1/s1/f/h29H2

SMILES:

c1ccc(cc1)C(c1ccccc1)([C@@H]1(CCN(CCc2ccc3c(CCO3)c2)C1))C(N)=O

Properties:

Formula:	C28H30N2O2	Atoms:	33
Molecular Weight:	426.55	Rotatable Bonds:	7
H-bond Acceptors:	4	H-bond Donors:	0
logP:	4.5957

Targets:

Name	Uniprot ID	Source	References	Interaction
Muscarinic acetylcholine receptor M1	ACM1_HUMAN	BindingDB	-	shows
Muscarinic acetylcholine receptor M2	ACM2_HUMAN	BindingDB	-	shows
Muscarinic acetylcholine receptor M3	ACM3_HUMAN	SuperTarget	-	shows
Muscarinic acetylcholine receptor M4	ACM4_HUMAN	BindingDB	-	shows
Muscarinic acetylcholine receptor M5	ACM5_HUMAN	BindingDB	-	shows

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Synonyms:

133099-04-4

2-[(3S)-1-[2-(2,3-dihydro-1-benzofuran-5-yl)ethyl]pyrrolidin-3-yl]-2,2-di(phenyl)acetamide

2-[(3S)-1-[2-(2,3-dihydro-1-benzofuran-5-yl)ethyl]pyrrolidin-3-yl]-2,2-dip

CHEBI:391960

D03654

Darifenacin

Darifenacin (USAN/INN)

DB00496

Emselex

Enablex

LS-187359

NCGC00168775-01

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ATC-Codes:

G04BD10

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Side-Effects:

Side-Effect	Frequency
palpitations	0.0010
hallucinations	0.0010
hypersensitivity	0.0010
confusion	0.0010
angioedema	0.0010
rhinitis	0
tachycardia	0
sweating	0
cerebrovascular accident	0
pharyngitis	0
pruritus	0
ulcerative stomatitis	0
sinusitis	0
urinary tract infection	0
vaginitis	0
dry eyes	0
thinking abnormal	0
dry skin	0
sgot increased	0
peripheral edema	0
urinary retention	0
dry mouth	0
weight gain	0
vomiting	0
abnormal vision	0
insomnia	0
pain	0
nausea	0
dizziness	0
diarrhea	0
cough	0
constipation	0
bronchitis	0
benign prostatic hyperplasia	0
back pain	0
asthenia	0
arthralgia	0
somnolence	0
dyspepsia	0
irritability	0
irritable bowel syndrome	0
influenza	0
impotence	0
hypertension	0
headache	0
flatulence	0
rash	0
edema	0
abdominal pain	0

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