Drug Details

Name:

Irl 1620

PubChem ID:

16130933

Pathway:

Show KEGG pathways

InChI:

InChI=1/C86H117N17O27/c1-11-44(7)71(84(127)100-63(86(129)130)35-50-39-88-54-21-17-16-20-53(50)54)103-85(128)72(45(8)12-2)102-82(125)62(38-69(114)115)98-78(121)57(32-42(3)4)96-80(123)60(36-51-40-87-41-89-51)95-73(116)46(9)91-77(120)58(33-48-18-14-13-15-19-48)97-79(122)59(34-49-22-24-52(104)25-23-49)99-83(126)70(43(5)6)101-74(117)47(10)90-75(118)55(26-29-65(106)107)93-76(119)56(27-30-66(108)109)94-81(124)61(37-68(112)113)92-64(105)28-31-67(11

SMILES:

Properties:

Formula:	C86H117N17O27	Atoms:	130
Molecular Weight:	1820.95	Rotatable Bonds:	70
H-bond Acceptors:	44	H-bond Donors:	0
logP:	4.5895

Targets:

Name	Uniprot ID	Source	References	Interaction
Endothelin B receptor	EDNRB_RAT	PROMISCUOUS	PMID 9771913	shows
Endothelin B receptor-like protein 2	ETBR2_RAT	PROMISCUOUS	PMID 9771913	shows
Phospholipase D1	PLD1_RAT	PROMISCUOUS	PMID 9756390	shows
Phospholipase D2	PLD2_RAT	PROMISCUOUS	PMID 9756390	shows
Phospholipase D3	PLD3_RAT	PROMISCUOUS	PMID 9756390	shows

enlarge table

Synonyms:

142569-99-1

Endothelin-1 (8-21), succinyl-(glu(9),ala(11,15))-

Irl 1620

Irl-1620

L-Tryptophan,

L-Tryptophan, N-(3-carboxy-1-oxopropyl)-L-alanyl-L-alpha-glutamyl-L-alpha-glutamyl-L-alanyl-L-valyl-L-tyrosyl-L-tyrosyl-L-alanyl-L-histidyl-L-leucyl-L-alpha-aspartyl-L-isoleucyl-L-isoleucyl-

LS-184750

NCGC00167326-01

Succinyl-(glu(9),ala(11,15))-endothelin-1 (8-21)

Succinyl-(glutamyl(9)-alanyl(11,15))-endothelin-1 (8-21)

enlarge table