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    Trek
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    Barium Cation



    Inhibition of:
    TREK: >1000000 nM (ic50)
    Synonymous names
    barium cation
    BARIUM ION
    AC1L2XJH
    Ba+2
    Ba2+
    barium(ii) ion
    Ba++
    HMDB04142
    C13881
    Barium (II) ion
    barium(2+)
    CHEBI:37136
    UNII-V645272HLN
    Ba(2+)
    AR-1H7770
    I14-115798
    Barium, ion (Ba2+)
    Smiles[Ba+2]
    104810 
     
    FormulaBa+2
    Molweight137.327
    Heavy Atoms1
    Rotatable Bonds0
    H-bond donors0
    H-bond Acceptors 0
    Cluster numberNo cluster with more than 3 Compounds available
    Vendors
    AAA Chemistry
    ABI Chem
    IS Chemical Technology


    Dexniguldipine



    Inhibition of:
    TREK: 750 nM (ic50)
    Synonymous names
    Dexniguldipine
    Niguldipinum
    NIGULDIPINE
    Niguldipino
    AC1L1B0Z
    Niguldipine(+)
    CHEMBL65305
    CTK6I8157
    SureCN245993
    HMS1791F17
    HMS2089H19
    HMS1989F17
    C11236
    DNC003951
    L001049
    KBioSS_000115
    KBioGR_000115
    BSPBio_001395
    CHEBI:216446
    KBio2_005251
    KBio2_002683
    KBio2_000115
    KBio3_000230
    KBio3_000229
    IDI1_033865
    Bio2_000595
    AG-K-58170
    Bio2_000115
    QTL1_000061
    B8509-035
    NCI60_005267
    NCGC00163135-04
    NCGC00163135-03
    NCGC00163135-02
    NCGC00163135-01
    102993-22-6
    BRD-A62336480-001-02-5
    3-(4,4-diphenylpiperidin-1-yl)propyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
    5-O-[3-(4,4-diphenylpiperidin-1-yl)propyl] 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
    Smiles
    CC1=C(C(C(=C(N1)C)C(=O)OCCCN2CCC(CC2)(C3=CC=CC=C3)C4=CC=CC=C4)C5=CC(=CC=C5)[N+](=O)[O-])C(=O)OC
    1236 
     
    FormulaC36H39N3O6
    Molweight609.711
    Heavy Atoms45
    Rotatable Bonds11
    H-bond donors1
    H-bond Acceptors 8
    Cluster numberCluster612
    Vendors
    ABI Chem
    Angene Chemical
    Chembase.cn


    Neoperidole


    Show similar structuresShow docking results

    Inhibition of:
    hERG: 18 nM (ic50)
     54.6 nM (ic50)
     1700 nM (ic50)
     7300 nM (ic50)
    TREK: 354 nM (ic50)
    Metabolism
    Extrarenal fraction (Q0)Elimination half-life (EHL)
    150h
    Synonymous names
    Neoperidole
    Pimozidum
    Primozida
    pimozide
    Halomonth
    pimozida
    Antalon
    Opiran
    Orap
    Pharmascience Brand of Pimozide
    Orap forte
    Janssen Brand of Pimozide
    AC1Q4NM9
    AC1L27SR
    ASTA Medica Brand of Pimozide
    CHEMBL1423
    M828
    Prestwick_395
    AC1Q4M09
    Pimozida [INN-Spanish]
    SureCN41584
    UNII-1HIZ4DL86F
    Primozida [INN-Spanish]
    HMS501D08
    CTK8G2428
    Pimozidum [INN-Latin]
    R6238
    DB01100
    CID16362
    P1793_SIGMA
    Tocris-0937
    BIDD:GT0435
    Orap (TN)
    HMS1989H21
    D00560
    HMS3267E19
    CCRIS 9172
    HMS1921H19
    C07566
    HMS3262N14
    C28H29F2N3O
    HMS1791H21
    HMS2231P23
    CHEBI:8212
    SPECTRUM1501134
    HMS1568N18
    HMS2095N18
    HMS2092F09
    HMS2089C11
    NSC170984
    NSC757854
    DAP000316
    R-6238
    R 6238
    D010868
    Spectrum_000445
    Pimozide (JAN/USP/INN)
    DSSTox_CID_3474
    P 1793
    L000494
    KBioGR_000720
    DSSTox_GSID_23474
    CCG-36461
    BSPBio_002941
    CCG-35918
    BSPBio_001439
    Lopac-P-1793
    BSPBio_000276
    KBioSS_000925
    LS-33236
    CCG-39728
    NCIMech_000356
    Prestwick1_000308
    Spectrum4_000420
    Prestwick0_000308
    Spectrum3_001451
    DSSTox_RID_77042
    McN-JR 6238
    Spectrum2_001026
    Prestwick3_000308
    SPBio_002495
    Pimozide [USAN:INN:BAN:JAN]
    McN-JR-6238
    Prestwick2_000308
    Spectrum5_001308
    SPBio_001211
    NINDS_000386
    CHEBI:464141
    AB00052215
    NSC 170984
    NSC-757854
    NSC-170984
    KBio3_002441
    KBio2_006061
    Pimozide (JP16/USP/INN)
    Pimozide [USAN:USP:INN:BAN:JAN]
    DivK1c_000386
    KBio2_003493
    BPBio1_000304
    KBio2_000925
    Lopac0_000946
    KBio1_000386
    MLS001077311
    AG-E-51364
    BRN 0729089
    MLS000028410
    EU-0100946
    BCBcMAP01_000043
    SMP1_000241
    SMR000058385
    IDI1_000386
    MLS002702058
    Tox21_301586
    Tox21_110224
    NCGC00024888-02
    NCGC00015802-07
    NCGC00024888-07
    NCGC00015802-13
    NCGC00015802-04
    NCGC00024888-01
    NCGC00015802-06
    NCGC00024888-06
    NCGC00015802-12
    NCGC00015802-02
    2062-78-4
    NCGC00022282-03
    NCGC00015802-05
    NCGC00024888-05
    NCGC00015802-11
    NCGC00015802-01
    NCGC00255294-01
    NCGC00016601-01
    NCGC00015802-03
    NCGC00024888-04
    NCGC00015802-10
    NCGC00015802-16
    NCGC00015802-15
    NCGC00024888-03
    NCGC00015802-09
    NCGC00015802-14
    NCGC00015802-08
    EINECS 218-171-7
    Pharmakon1600-01501134
    CAS-2062-78-4
    2-Benzimidazolinone,4-bis(p-fluorophenyl)butyl]-4-piperidyl]-
    MolPort-001-736-597
    117210-EP2272537A2
    117210-EP2298776A1
    117210-EP2295061A1
    117210-EP2275420A1
    WLN: T56 BMVNJ D- DT6NTJ A3YR DF&R DF
    5-24-02-00367 (Beilstein Handbook Reference)
    BRD-K01292756-001-06-0
    1-(4,4-Bis(p-fluorophenyl)butyl)-4-(2-oxo-1-benzimidazolinyl)piperidine
    1-[4,4-Bis(p-fluorophenyl)butyl]-4-(2-oxo-1-benzimidazolinyl)piperidine
    1-(1-(4,4-Bis(p-fluorophenyl)butyl)-4-piperidyl)-2-benzimidazolinone
    1-[1-[4,4-Bis(p-fluorophenyl)butyl]-4-piperidyl]-2-benzimidazolinone
    2H-Benzimidazol-2-one,4-bis(4-fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-
    2-Benzimidazolinone, 1-[1-[4,4-bis(p-fluorophenyl)butyl]-4-piperidyl]-
    2-Benzimidazolinone, 1-(1-(4,4-bis(p-fluorophenyl)butyl)-4-piperidyl)-
    3-[1-[4,4-bis(4-fluorophenyl)butyl]piperidin-4-yl]-1H-benzimidazol-2-one
    1-{1-[4,4-bis(4-fluorophenyl)butyl]piperidin-4-yl}-1,3-dihydro-2H-benzimidazol-2-one
    1-[1-[4,4-bis(4-Fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one
    1-[1-[4,4-Bis(4-fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-2H- benzimidazol-2-one
    2H-Benzimidazol-2-one, 1-(1-(4,4-bis(4-fluorophenyl)butyl)-4-piperidinyl)-1,3-dihydro-
    2H-Benzimidazol-2-one, 1-[1-[4,4-bis(4-fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-
    1-{1-[4,4-bis(4-fluorophenyl)butyl]piperidin-4-yl}-2,3-dihydro-1H-1,3-benzodiazol-2-one
    2-Benzimidazolinone,1-[1-[4,4-bis(p-fluorophenyl)butyl]-4-piperidyl]- (7CI,8CI);1-(1-(4,4-Bis(4-fluorophenyl)butyl)-4-piperindinyl)-1,3-dihydro-2H-benzimidazol-2-one;1-[1-[4,4-Bis(p-fluorophenyl)butyl
    SmilesC1CN(CCC1N2C3=CC=CC=C3NC2=O)CCCC(C4=CC=C(C=C4)F)C5=CC=C(C=C5)F
    16362 
     
    12729675, 12747773, 12190308, 12873512, 19534531, 15324906,
    FormulaC28H29F2N3O
    Molweight461.546
    Heavy Atoms34
    Rotatable Bonds7
    H-bond donors1
    H-bond Acceptors 4
    Cluster numberNo cluster with more than 3 Compounds available
    Vendors
    ABI Chem
    AK Scientific, Inc. (AKSCI)
    Angene Chemical
    Chembase.cn
    ChemFrog
    ChemMol
    EMD Biosciences
    MP Biomedicals
    Sigma-Aldrich


    Dalfampridine


    Show similar structuresShow docking results

    Inhibition of:
    hERG: 4400000 nM (ic50)
    TREK: >1000000 nM (ic50)
    Synonymous names
    Dalfampridine
    fampridinum
    fampridina
    gamma-Aminopyridine
    Fampridine
    Pymadine
    Neurelan
    Dalfampridine-ER
    Ampyra
    FAMPYRA
    Avitrol
    Pymadin
    p-Aminopyridine
    Ampydin
    Fampridine-PR
    Fampridine SR
    Amaya
    Fampridine-SR
    4-Pyridinamine
    4-aminopyridine
    4 Aminopyridine
    4-Aminopyridine Sustained Release
    4-Pyridylamine
    4 Aminopyridine Sustained Release
    pyridin-4-ylamine
    .gamma.-Aminopyridine
    4-Pyridinamine; Fampridine
    Dalfampridine (USAN)
    Sustained Release, 4-Aminopyridine
    Amino-4-Pyridine
    PYRIDINE,4-AMINO
    pyridin-4-amine
    AC1Q52BM
    Amino-4 pyridine
    AC1L1C3R
    Dalfampridine [USAN]
    VMI103
    4-AP
    C5H6N2
    4 AP
    PubChem1281
    UPCMLD-DP125
    A106
    Fampridine (INN)
    Neurelan (TN)
    SureCN53483
    CID1727
    ARONIS25052
    Avitrol 200
    pyridin-4-yl-amine
    UNII-BH3B64OKL9
    N07XX07
    4-Pyridinamine, 4-Pyridylamine
    Compound 1861
    Fampridine [USAN:INN]
    BIIB-041
    Ampyra (TN)
    A0414
    Fampridine (USAN/INN)
    HMS501M14
    Fampyra (TN)
    CTK0J1462
    Phillips 1861
    4-Aminopyridine 10
    VMI-103
    SureCN291100
    NSC15041
    CHEMBL284348
    VMI 103
    Mi-W-3
    Philips 1861
    Tocris-0940
    Pimadin (free base)
    EL-970
    A78403_ALDRICH
    HMS1361O04
    HMS3267E21
    HSDB 6037
    WLN: T6NJ DZ
    D04127
    HMS3260G05
    HMS2092F05
    C13728
    HMS2234N24
    SPECTRUM1501130
    HMS1989O04
    4(1H)-Pyridinimine
    HMS1921H15
    HMS1791O04
    SBB004393
    BBL009925
    NSC757845
    HC150041
    DNC000635
    Prc 1237
    36687_RIEDEL
    STK298717
    DCL000671
    Pyridine, 4-amino-
    CHEBI:34385
    A 0152
    D015761
    Spectrum_000155
    DSSTox_CID_3870
    36687_FLUKA
    nchem.892-comp4
    275875_ALDRICH
    VMI-10-3
    CCG-39031
    AK-77153
    Lopac-A-0152
    KBioSS_000635
    KBioSS_000282
    ANW-75388
    NSC-15041
    KBioGR_001505
    TL8003344
    VMI 10-3
    KBioGR_000282
    DSSTox_GSID_23870
    NSC 15041
    BSPBio_001562
    KB-36586
    AB1004971
    Caswell No. 038
    Spectrum2_001413
    DSSTox_RID_77212
    BB_SC-6974
    T7101061
    Spectrum5_001501
    NINDS_000572
    Spectrum4_001013
    SPBio_001486
    Spectrum3_000914
    NSC-757845
    AI3-52547
    ST45053817
    AM20061261
    LS-130202
    EPA Pesticide Chemical Code 069201
    KBio3_000564
    UPCMLD-DP125:001
    KBio2_000635
    KBio3_000563
    Lopac0_000032
    KBio2_000282
    KBio2_005771
    KBio1_000572
    KBio2_005418
    AKOS000119896
    KBio2_003203
    KBio3_001888
    RCRA waste no. P008
    DivK1c_000572
    KBio2_002850
    FT-0083754
    Bio1_000353
    SMR000058211
    MLS000069400
    EU-0100032
    Bio2_000762
    BRN 0105782
    Bio2_000282
    IDI1_034032
    AG-L-63957
    Bio1_001331
    IDI1_000572
    AG-F-69554
    Bio1_000842
    AG-C-18560
    Tox21_200793
    Tox21_110065
    504-24-5
    NCGC00024890-03
    NCGC00015009-10
    NCGC00024890-08
    NCGC00015009-01
    NCGC00015009-02
    NCGC00024890-02
    NCGC00015009-09
    NCGC00024890-07
    NCGC00258347-01
    NCGC00024890-01
    NCGC00015009-07
    NCGC00024890-06
    NCGC00015009-14
    NCGC00015009-12
    NCGC00015009-06
    NCGC00024890-05
    NCGC00015009-13
    NCGC00024890-10
    NCGC00015009-08
    NCGC00015009-05
    NCGC00024890-04
    NCGC00015009-11
    NCGC00024890-09
    NCGC00015009-03
    NCGC00015009-04
    EINECS 207-987-9
    CAS-504-24-5
    29212-32-6
    SDCCGMLS-0066228.P001
    Pharmakon1600-01501130
    p-Aminopyridine [UN2671] [Poison]
    MolPort-000-146-022
    4-Amino Piperidine;piperidin-4-amine;4-Aminopiperidine, 97%;
    79676-EP2305696A2
    68146-EP2284157A1
    79676-EP2305695A2
    p-Aminopyridine [UN2671] [Poison]
    AC-907/25014071
    68146-EP2269990A1
    68146-EP2380872A1
    68146-EP2308874A1
    79676-EP2305698A2
    68146-EP2298731A1
    79676-EP2305697A2
    68146-EP2289894A2
    5-22-09-00106 (Beilstein Handbook Reference)
    [J.Pharmacol.Exp.Ther. 275:864 (1995)]
    InChI=1/C5H6N2/c6-5-1-3-7-4-2-5/h1-4H,(H2,6,7
    SmilesC1=CN=CC=C1N
    1727 
     
    15324906,
    FormulaC5H6N2
    Molweight94.1145
    Heavy Atoms7
    Rotatable Bonds0
    H-bond donors1
    H-bond Acceptors 2
    Cluster numberNo cluster with more than 3 Compounds available
    Vendors
    ABBLIS Chemicals
    ABI Chem
    AK Scientific, Inc. (AKSCI)
    AKos Consulting & Solutions
    Ambinter
    Angene Chemical
    Angene International
    Anward
    Apexmol
    Ark Pharm, Inc.
    Aronis
    Calbiochem
    CAPOT
    Chembase.cn
    Chembo
    ChemExper Chemical Directory
    ChemFrog
    Chemical Synthesis Database
    ChemMol
    Enamine
    FINETECH
    Hangzhou Trylead Chemical Technology
    MIC Scientific
    MolPort
    MP Biomedicals
    Oakwood Products
    R&D Chemicals
    Sigma-Aldrich
    Specs
    TCI (Tokyo Chemical Industry)
    TimTec
    Vitas-M Laboratory


    AC1L54N5



    Inhibition of:
    TREK: 24800 nM (ic50)
    Synonymous names
    AC1L54N5
    SureCN676914
    HMS1989D19
    L-(cis)-diltiazem
    HMS1791D19
    BSPBio_001357
    Lopac-D-2521
    ACN-S002488
    NCGC00016818-04
    NCGC00016818-01
    NCGC00015332-02
    NCGC00015332-01
    NCGC00163133-03
    CAS-33286-22-5
    BRD-K81029756-001-02-8
    [(2R,3R)-5-(2-dimethylaminoethyl)-2-(4-methoxyphenyl)-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl] acetate
    (+)-5-[2-(Dimethylamino)ethyl]-cis-2,3-dihydro-3-hydroxy-2-(p-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one acetate (ester)
    SmilesCC(=O)OC1C(SC2=CC=CC=C2N(C1=O)CCN(C)C)C3=CC=C(C=C3)OC
    198107 
     
    FormulaC22H26N2O4S
    Molweight414.518
    Heavy Atoms29
    Rotatable Bonds7
    H-bond donors0
    H-bond Acceptors 6
    Cluster numberNo cluster with more than 3 Compounds available
    Vendors
    ABI Chem
    Acorn PharmaTech


    Pseudotheophylline



    Inhibition of:
    TREK: 486000 nM (ic50)
    Metabolism
    Extrarenal fraction (Q0)Elimination half-life (EHL)
    0.042h
    Synonymous names
    Pseudotheophylline
    Dimethylxanthine
    Theophylline aminoacetate
    Bronchoparat
    Elixophyllin
    Elixophylline
    Chronophyllin
    Glycine Theophyllinate
    theophylline
    Parkophyllin
    Cetraphylline
    Theoconfin Continuous
    Theophylline solution
    aminophylline
    Bronchoretard
    Theophylline anhydrous
    Armophylline
    Liquophylline
    Labophylline
    SomophyllinT
    Lanophyllin
    Optiphyllin
    Duraphyllin
    SloPhyllin
    Synophylate
    Theocontin
    Doraphyllin
    Theophyline
    Medaphyllin
    Theophyllin
    Uniphyllin continus
    Maphylline
    Teofyllamin
    Aquaphyllin
    Uniphylline
    Bronkotabs
    Euphylline
    Uniphyllin
    Theograd
    Theospan
    Theonite
    Bronchodid Duracap
    Theostat
    Etheophyl
    Euphylong
    Talotren
    Theochron
    Elixomin
    Afonilum
    Theophyl
    Egifilin
    Elixicon
    Respicur
    Euphyllin
    Theacitin
    Duraphyl
    Theodrip
    Quadrinal
    Theovent
    Diffumal
    Bronkodyl
    Accurbron
    Spophyllin retard
    Pulmidur
    Theoclear
    ConstantT
    Xantivent
    Theolixir
    Theotard
    Xanthium
    Sustaire
    Theolair
    Aerolate
    Teofilina
    Bilordyl
    Theoplus
    Theocin
    Teolair
    Mudrane
    Tesona
    Asbron
    Teonova
    Somophyllin CRT
    Tefamin
    Asmalix
    Respbid
    Solosin
    Respid
    Theophylline-SR
    Aerobin
    Theokin
    Nuelin
    Uniphyl
    Elixex
    Hylate
    Elixophyllin SR
    Unifyl
    Afonilm
    Austyn
    Theopek
    Unilong
    Theolix
    Theobid Duracap
    Quibron
    Theophylline-Supplied by Selleck Chemicals
    Theodur
    Theobid
    Theofol
    Physpan
    Afonilum Retard
    Somophyllin-CRT
    Theodel
    Teosona
    Somophyllin T
    component of Primatene
    Theo-Organidin
    LASMA
    Somophyllin-t
    Pulmo-Timelets
    Somophyllin-DF
    Theophylline, anhydrous
    Theal tablets
    LaBID
    Asmax
    Theoclair-SR
    component of Dicurin Procaine
    Theophyl-SR
    Slo-phyllin
    Acet-theocin
    Theolair-SR
    Bronkodyl SR
    Choledyl SA
    Aerolate SR
    Theoclear LA
    Quibron TSR
    Aerolate III
    Slo Phyllin
    Constant-T
    Quibron-T
    Nuelin SA
    Theo-Nite
    component of Theo-Organidin
    Quibron T
    Constant T
    THEOBID JR
    Theodur G
    Theo-DS
    Theo Dur
    Slo-bid
    Pro-vent
    Theo-Dur-Sprinkle
    Telb-DS
    Theona P
    Theodur Dry Syrup
    Theo-dur
    Theo-Sav
    Uni-Dur
    Telbans Dry Syrup
    T-Phyl
    Theophylline (anhydrous)
    Elixophyllin(e)
    Theo24
    2a3a
    Quibron-T/SR
    CHEMBL190
    Quibron T-SR
    Dimethylxanthine, Theo-Dur, Theophylline
    Quibron T/SR
    Quibron T SR
    Theostat 80
    1,3 Dimethylxanthine
    Theoclear-80
    Theobid Jr.
    Nuelin S.A
    theo von ct
    AC1L1D1F
    Theoclear 80
    Theal tabl.
    1,3-Dimethylxanthine
    SureCN4915
    PubChem9695
    Teofilina [Polish]
    Elixophyllin (TN)
    Xanthine,3-dimethyl-
    Theophyl-225
    Theo-24
    Theoclear-200
    C7H8N4O2
    Theo-11
    UPCMLD-DP123
    Theo 24
    KSC491S8L
    Synophylate-L.A. Cenules
    Teocen 200
    Theolair (TN)
    NSC2066
    CID2153
    ARONIS25346
    N1442
    S1621_Selleck
    HMDB01889
    von ct, theo
    T0179
    CTK3J1985
    Nuelin S.A.
    Uniphyl (TN)
    ct, theo von
    HMS500K05
    BIDD:GT0151
    T9031_SIGMA
    Theophylline (JP16)
    DB00277
    BIDD:ER0557
    T7770_SIGMA
    Theophylline (JP15)
    T4924_SIGMA
    T1633_SIGMA
    LS-241
    HMS1921E03
    HSDB 3399
    CCRIS 4729
    D00371
    HMS3259O06
    SPECTRUM1500568
    X 115
    HMS2092M05
    C07130
    Theophylline-[8-3H
    nchembio.273-comp2
    HMS2233E16
    HMS2089A06
    DAP000002
    NSC-2066
    Quibron-t (TN)
    SureCN8595167
    SureCN8312163
    BBL023514
    Theodur G (TN)
    NSC 2066
    ST024762
    GS 2591A
    STK397040
    NSC757346
    L000595
    DSSTox_CID_1336
    Spectrum_001038
    UNII-0I55128JYK
    CHEBI:28177
    D013806
    8-(2-Furyl)theophylline
    KBioGR_000785
    CPD-12479
    DSSTox_GSID_21336
    BSPBio_002363
    CCG-20301
    BSPBio_000945
    AB1009249
    BSPBio_000719
    AC-20328
    KBioSS_001518
    Prestwick3_000873
    SPBio_002640
    ZINC18043251
    Prestwick0_000873
    Prestwick3_000820
    SPBio_000823
    Spectrum5_001232
    Prestwick0_000820
    DSSTox_RID_76090
    Prestwick2_000873
    Spectrum4_000353
    Prestwick2_000820
    Spectrum3_000672
    NINDS_000203
    Prestwick1_000873
    T5889051
    Spectrum2_000842
    SPBio_002866
    Prestwick1_000820
    AI3-50216
    NSC-757346
    AB00052106
    Lopac0_000014
    KBio2_006654
    DivK1c_000203
    UPCMLD-DP123:001
    KBio2_004086
    PDSP2_001218
    1H-purine-2,6-dione
    BPBio1_001041
    KBio2_001518
    PDSP2_001002
    BPBio1_000791
    Xanthine, 1,3-dimethyl-
    KBio1_000203
    PDSP1_001234
    AKOS005434016
    PDSP1_001018
    KBio3_001583
    AKOS000120961
    Theoclear L.A.-130
    MLS000069390
    SMP1_000291
    Theo-24 (TN)
    IDI1_000203
    CPD000058537
    2,6-Dihydroxy-1,3-dimethylpurine
    AG-F-71381
    SMR000058537
    MLS002153487
    MLS004491910
    SAM002554935
    MLS002152943
    BCBcMAP01_000071
    I14-16783
    58-55-9
    NCI60_001736
    Tox21_110827
    Tox21_300028
    Tox21_202375
    CAS-58-55-9
    NCGC00018117-19
    NCGC00022112-10
    NCGC00018117-06
    NCGC00018117-12
    NCGC00022112-03
    NCGC00018117-18
    NCGC00022112-09
    NCGC00018117-05
    NCGC00259924-01
    NCGC00018117-11
    NCGC00018117-16
    NCGC00018117-17
    NCGC00022112-08
    NCGC00018117-04
    NCGC00254040-01
    NCGC00018117-10
    NCGC00018117-07
    NCGC00018117-15
    NCGC00022112-07
    NCGC00018117-03
    NCGC00022112-12
    NCGC00018117-09
    NCGC00018117-01
    NCGC00018117-14
    NCGC00022112-05
    NCGC00018117-02
    NCGC00018117-20
    NCGC00022112-11
    NCGC00018117-08
    NCGC00018117-13
    NCGC00022112-04
    EINECS 200-385-7
    SDCCGMLS-0066620.P001
    46157-00-0
    Pharmakon1600-01500568
    75448-53-2
    56645-32-0
    111079-49-3
    MolPort-001-002-058
    6461-EP2281813A1
    6461-EP2301933A1
    6461-EP2308562A2
    6461-EP2280006A1
    6461-EP2298305A1
    MolPort-001-737-342
    6461-EP2305640A2
    6461-EP2272844A1
    6461-EP2295434A2
    6461-EP2305219A1
    6461-EP2272841A1
    6461-EP2286811A1
    6461-EP2301937A1
    6461-EP2272835A1
    6461-EP2314590A1
    6461-EP2281815A1
    6461-EP2301936A1
    6461-EP1441224A2
    6461-EP2311827A1
    WLN: T56 BM DN FNVNVJ F1 H1
    1,3-dimethyl-7H-purine-2,6-dione
    83377-EP2371823A1
    Purine-2,3H)-dione, 1,3-dimethyl-
    1,3-dimethyl-1,3,7-trihydropurine-2,6-dione
    Purine,6(1H,3H)-dione, 1,3-dimethyl-
    3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione
    1H-Purine-2, 3,7-dihydro-1,3-dimethyl-
    1,3-Dimethyl-3,7-dihydro-1H-purine-2,6-dione
    1,3-dimethyl-3,9-dihydro-1H-purine-2,6-dione
    1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydropurine
    BRD-K97799481-002-03-6
    BRD-K97799481-001-02-0
    3,7-dihydro-1,3-dimethyl-1H- purine-2,6-dione
    Purine-2,6(1H,3H)-dione, 1,3-dimethyl-
    1H-Purine-2,6-dione, 3,9-dihydro-1,3-dimethyl-
    1H-Purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-
    A3133D49-AAB6-49A1-B60B-B5198F327D3F
    InChI=1/C7H8N4O2/c1-10-5-4(8-3-9-5)6(12)11(2)7(10)13/h3H,1-2H3,(H,8,9
    1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydropurine; 1,3-Dimethylxanthine; 3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione
    SmilesCN1C2=C(C(=O)N(C1=O)C)NC=N2
    2153 
     
    FormulaC7H8N4O2
    Molweight180.164
    Heavy Atoms13
    Rotatable Bonds0
    H-bond donors1
    H-bond Acceptors 3
    Cluster numberNo cluster with more than 3 Compounds available
    Vendors
    ABBLIS Chemicals
    ABI Chem
    AK Scientific, Inc. (AKSCI)
    AKos Consulting & Solutions
    Ambinter
    Angene Chemical
    ApexBio Technology
    Aronis
    CAPOT
    Chembase.cn
    ChemExper Chemical Directory
    ChemFrog
    ChemMol
    Enamine
    Hangzhou APIChem Technology
    IS Chemical Technology
    King Scientific
    MolPort
    MP Biomedicals
    NIH Clinical Collection
    Selleck Chemicals
    Sigma-Aldrich
    TCI (Tokyo Chemical Industry)
    TimTec
    Vitas-M Laboratory
    ZINC


    Levoamlodipine



    Inhibition of:
    TREK: 430 nM (ic50)
    Metabolism
    Extrarenal fraction (Q0)Elimination half-life (EHL)
    0.8540h
    Synonymous names
    Levoamlodipine
    amlodipine
    Amlodipine besilate
    Amlodipino
    Amlodipinum
    Amlopres
    Racemic Amlodipine
    Amlocard
    Intervask
    Amlodis
    Norvasc
    Lipinox
    Coroval
    Caduet
    AMLODIPINE BASE
    Amvaz
    Amlor
    Istin
    Amlodipine-Supplied by Selleck Chemicals
    Amlodipine Free Base
    Istin;Norvasc;Caduet;Norvasc
    Amlodipino [Spanish]
    Amlodipinum [Latin]
    AC1Q32ZS
    CHEMBL1491
    Amlodipine (INN)
    AC1L1D26
    K577
    R,S)-Amlodipine
    ()-Amlodipine
    SureCN26478
    CID2162
    Norvasc (TN)
    S1905_Selleck
    Amlodipine [INN:BAN]
    HMDB05018
    DB00381
    BIDD:GT0810
    D07450
    CHEBI:2668
    HMS3394N03
    C06825
    HMS2231K08
    BCPP000403
    HMS2089H07
    HMS2052N03
    Amlodipine, Istin, Norvasc, Caduet
    AC-4535
    DAP000139
    BBL023710
    ABP000734
    A800681
    BCP9000295
    AB2000364
    KBioGR_001643
    BSPBio_002727
    Spectrum5_001550
    Spectrum4_001132
    Spectrum3_001004
    Spectrum2_000486
    SPBio_000351
    CCG-101157
    UNII-1J444QC288
    LS-131183
    KBio3_001947
    I14-0798
    AKOS015843475
    SAM001246705
    CPD000469198
    UK-4834011
    MLS001401409
    SMR000469198
    NCGC00165957-04
    NCGC00165957-03
    NCGC00165957-05
    NCGC00165957-02
    Ambap88150-42-9
    NCGC00165957-01
    88150-42-9
    MolPort-001-792-963
    -3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-1,4-dihydropyridine
    2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)
    BRD-A22032524-074-03-2
    BRD-A22032524-074-02-4
    88150-47-4 (maleate (1:1))
    R,S)-Amlodipine; ()-Amlodipine; 2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)
    O3-ethyl O5-methyl 2-(2-azanylethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
    2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic acid O3-ethyl ester O5-methyl ester
    3-O-ethyl 5-O-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
    3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
    3-ethyl 5-methyl 2-{[(2-aminoethyl)oxy]methyl}-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
    3-Ethyl-5-methyl (+-)-2-(2-aminoethoxymethyl)-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate
    3-Ethyl-5-methyl (+-)-2-((2-aminoethoxymethyl)-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate
    3-Ethyl-5-methyl ( -)-2-((2-aminoethoxymethyl)-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate
    3,5-Pyridinedicarboxylic acid, 2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester
    3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester
    3-Ethyl-5-methyl ( -)-2-((2-aminoethoxy)methyl)-4-(2-chlorphenyl)-1,4-dihydro-6-methyl-3,5-pyridindicarboxylat
    3-Ethyl-5-methyl (+-)-2-((2-aminoethoxy)methyl)-4-(2-chlorphenyl)-1,4-dihydro-6-methyl-3,5-pyridindicarboxylat
    3-Ethyl-5-methyl (.+/-.)-2-[(2-aminoethoxy)methyl]-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate
    SmilesCCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN
    2162 
     
    FormulaC20H25ClN2O5
    Molweight408.876
    Heavy Atoms28
    Rotatable Bonds10
    H-bond donors2
    H-bond Acceptors 7
    Cluster numberNo cluster with more than 3 Compounds available
    Vendors
    ABBLIS Chemicals
    ABI Chem
    Active Biopharma
    AK Scientific, Inc. (AKSCI)
    AKos Consulting & Solutions
    Alsachim
    Amadis Chemical
    Ambinter
    BioChemPartner
    Chembase.cn
    ChemFrog
    ChemMol
    Hangzhou APIChem Technology
    IS Chemical Technology
    NIH Clinical Collection
    Selleck Chemicals
    Vitas-M Laboratory


    Merrillite



    Inhibition of:
    TREK: 659000 nM (ic50)
    Synonymous names
    Merrillite
    Rheinzink
    zincum
    zincide
    Zinc preparation
    cinc
    ZINC
    Zink
    Granular zinc
    Jasad
    Zinc powder
    Zinc nitrate solution
    Blue powder
    Znn
    Zinc ashes
    zinc anion
    Zinc and compounds
    Zinc dust
    ZN1
    Emanay zinc dust
    Lead refinery vacuum zinc
    Zinc, elemental
    Zinc standard for AAS
    30Zn
    AC1L2N4Y
    ZINC, DUST
    ACMC-1BKT7
    LS 6
    LS 2
    UNII-J41CSQ7QDS
    KSC377I7L
    Zinc (metallic)
    Zinc powder or zinc dust
    BCR110_FLUKA
    BCR109_FLUKA
    UN1436
    UN1435
    zinc(I) cation
    CTK2H7475
    zincide(-I)
    Z0015
    zinc(0)
    Asarco L 15
    Zinc ore concentrate (trace elements)
    DB01593
    Zn(0)
    HSDB 1344
    CCRIS 1582
    Zn(-)
    zincide(1-)
    Zn(+)
    14409_RIEDEL
    14409_ALDRICH
    14404_RIEDEL
    14404_ALDRICH
    31653_RIEDEL
    14401_RIEDEL
    14401_ALDRICH
    Zinc Powder 325 mesh
    Zinc(1+)
    02584_FLUKA
    CHEBI:37255
    CHEBI:37254
    CHEBI:30185
    31653_SIAL
    Zinc(1-)
    CHEBI:27363
    267635_ALDRICH
    356018_ALDRICH
    209988_ALDRICH
    267619_ALDRICH
    349410_ALDRICH
    578002_ALDRICH
    266361_ALDRICH
    324930_ALDRICH
    565148_ALDRICH
    266353_ALDRICH
    Zinc (fume or dust)
    499552_ALDRICH
    215503_ALDRICH
    AB1004144
    267929_ALDRICH
    Zinc (dust or fume)
    402583_ALDRICH
    ANW-56394
    215481_ALDRICH
    BP-11393
    266345_SIAL
    243477_SIAL
    243469_SIAL
    209988_SIAL
    LS-162822
    zinc(1+) ion
    AKOS015907403
    AG-G-95771
    I14-20513
    zinc ion (1+)
    Zinc, dust <10nm min
    7440-66-6
    ZINC, 99.9998%
    Zinc, ion (Zn1+)
    EINECS 231-175-3
    19229-95-9
    15176-26-8
    13982-39-3
    12793-53-2
    Zinc, ion (Zn 1-)
    298688-49-0
    199281-21-5
    195161-85-4
    Zinc ashes [UN1435] [Dangerous when wet]
    Zinc ashes [UN1435] [Dangerous when wet]
    Zinc powder or zinc dust [UN1436] [Dangerous when wet]
    Zinc powder or zinc dust [UN1436] [Dangerous when wet]
    Lead refinery vacuum zinc;Zinc (metallic);Zinc (dust or fume);zinc(0);F 2000 (metal);Asarco L 15;Electrowinningzinc Zinc;Nutrition,plantzinc Zinc;Zinc, elemental;Zn(II);Ecka 4;Rheinzink;NC-Zinc;Blue p
    Smiles[Zn]
    23994 
     
    FormulaZn
    Molweight65.38
    Heavy Atoms1
    Rotatable Bonds0
    H-bond donors0
    H-bond Acceptors 0
    Cluster numberNo cluster with more than 3 Compounds available
    Vendors
    ABBLIS Chemicals
    ABI Chem
    Achemica
    AKos Consulting & Solutions
    Ambinter
    Angene Chemical
    Anward
    BroadPharm
    Chembase.cn
    ChemFrog
    ChemMol
    IS Chemical Technology
    King Scientific
    MP Biomedicals
    Oakwood Products
    Sigma-Aldrich
    TCI (Tokyo Chemical Industry)


    Bupivacaine Monohydrochloride, Monohydrate



    Inhibition of:
    TREK: 113000 nM (ic50)
    Metabolism
    Extrarenal fraction (Q0)Elimination half-life (EHL)
    0.93.5h
    Synonymous names
    Bupivacaine liposome injectable suspension
    Bupivacaine Monohydrochloride, Monohydrate
    DepoBupivacaine
    Bupivacainum
    Bupivacaine Carbonate
    cBupivacaine
    bupivacaine
    Carbostesin
    Bupivacaina
    Transdur-Bupivacaine
    Sensorcaine
    Marcaine
    Bloqueina
    Marcaina
    Bupivan
    Sensorcaine-MPF
    Marcaine Spinal
    Exparel
    Bucaine
    Anekain
    Bupivacaine HCL
    Sensorcaine-MPF Spinal
    DL-Bupivacaine
    Marcaine HCL
    Bupivacaine HCL KIT
    AC1L1DRE
    AC1Q5LX4
    CHEMBL1098
    Bupivacaine (INN)
    R962
    Bupivacainum [INN-Latin]
    Bupivacaina [INN-Spanish]
    ( inverted exclamation markA)-bupivacaine
    CID2474
    Bupivacaine (USAN/INN)
    SKY0402
    SureCN25438
    LAC-43
    Bupivacaine [INN:BAN]
    C18H28N2O
    Bucaine (TN)
    Exparel (TN)
    CTK8B4736
    DB00297
    AH 250
    DUR-843
    Bupivacaine [USAN:INN:BAN]
    HMS2090F12
    D07552
    CHEBI:3215
    C07529
    HSDB 7790
    Bio-0886
    AC-2096
    SKY 0402
    LS-2222
    NSC119660
    DAP001229
    ST065773
    KST-1A4609
    L000695
    Spectrum_001524
    ANW-45984
    KBioSS_002004
    Win 11318
    KBioGR_001516
    AK-90074
    BSPBio_002607
    BSPBio_000270
    AR-1A0242
    Prestwick1_000305
    Spectrum4_001098
    Prestwick0_000305
    Spectrum3_000974
    SPBio_002489
    Spectrum2_001589
    SPBio_001558
    NINDS_000758
    Prestwick3_000305
    Prestwick2_000305
    Spectrum5_001483
    (+-)-Bupivacaine
    Win 11318 HCl
    AB00053674
    UNII-Y8335394RO
    LS-109841
    KBio2_004572
    KBio2_002004
    KBio1_000758
    DivK1c_000758
    AKOS001637202
    KBio3_001827
    BPBio1_000298
    KBio2_007140
    MLS001361336
    IDI1_000758
    SMR000058218
    AG-E-59395
    2180-92-9
    NCGC00178579-02
    NCGC00178579-01
    EINECS 253-911-2
    EINECS 218-553-3
    1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide
    15233-43-9
    1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
    38396-39-3
    1-Butyl-2',6'-pipecoloxylidide
    MolPort-004-955-820
    dl-1-Butyl-2',6'-pipecoloxylidide
    2-Piperidinecarboxamide, 1-butyl-N-(2,6-dimethylphenyl)-
    N-(2,6-dimethylphenyl)(1-butyl(2-piperidyl))carboxamide
    2',6'-Pipecoloxylidide, 1-butyl-
    (1)-1-Butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
    BRD-A01636364-003-05-2
    BRD-A01636364-003-08-6
    2-Piperidinecarboxamide, 1-butyl-N-(2,6-dimethylphenyl)-, (+-)-
    Anekain;2-Piperidinecarboxamide, 1-butyl-N-(2,6-dimethylphenyl)-, (+-)-;2-Piperidinecarboxamide, 1-butyl-N-(2,6-dimethylphenyl)-;1-Butyl-2,6-pipecoloxylidide;DL-Bupivacaine;Carbostesin;2180-92-9;1-but
    SmilesCCCCN1CCCCC1C(=O)NC2=C(C=CC=C2C)C
    2474 
     
    FormulaC18H28N2O
    Molweight288.428
    Heavy Atoms21
    Rotatable Bonds5
    H-bond donors1
    H-bond Acceptors 2
    Cluster numberCluster570
    Vendors
    AAA Chemistry
    ABI Chem
    AK Scientific, Inc. (AKSCI)
    AKos Consulting & Solutions
    Ambinter
    Angene Chemical
    Anward
    Ark Pharm, Inc.
    Chembase.cn
    ChemFrog
    ChemMol
    Hangzhou APIChem Technology
    Kingston Chemistry
    Oakwood Products
    TimTec


    Methylxanthine Theophylline



    Inhibition of:
    TREK: 377000 nM (ic50)
    Metabolism
    Extrarenal fraction (Q0)Elimination half-life (EHL)
    15.0h
    Synonymous names
    Methylxanthine theophylline
    Methyltheobromide
    Methyltheobromine
    Percutafeine
    Monohydrate Caffeine
    Caffedrine
    Monomethyl derivative of Theophylline
    Lanorinal
    Guaranine
    Hycomine Compound
    CAFFEINE ANHYDROUS
    Migergot
    Caffedrine Caplets
    Fiorinal
    caffeine
    Wigraine
    Enerjets
    Caffeina
    Coffeine
    Caffeine solution
    Durvitan
    Hycomine
    Coffeinum
    Orphengesic Forte
    Anhydrous caffeine
    caffenium
    Natural Caffeinum
    Cafcit
    Coffein
    Cafamil
    Miudol
    Maximum Strength Snapback Stimulant Powders
    Mateina
    Tirend
    Percoffedrinol N
    Theine
    Organex
    Kofein
    Koffein
    Nodaca
    Coffeinum Purrum
    Invagesic Forte
    Dexitac
    Ercatab
    cafeine
    Cafeina
    Vivarin
    GlaxoSmithKline Brand of Caffeine
    Cafipel
    Diurex
    Caffine
    Theophylline Me
    Caffein
    7-Methyltheophylline
    DHCplus
    Darvon compound
    Phensal
    Cafecon
    teina
    Caffeine Pure
    Stim
    Midol Maximum Strength
    Theobromine Me
    Anacin Maximum Strength
    Norgesic forte
    Dasin
    1-methyltheobromine
    Thein
    Caffeine, Monohydrate
    Nodoz Maximum Strength Caplets
    component of Cafergot
    CFF
    Synalgos-dc
    Coffeinum N
    Eldiatric C
    Alert-pep
    Caffeine, anhydrous
    Quick-Pep
    Quick Pep
    Dexitac Stay Alert Stimulant
    Caffeine, synthetic
    Keep Alert
    Wake-Up
    Passauer Brand of Caffeine
    Nix Nap
    7-methyl Theophylline
    DHC Plus
    Pep-Back
    Tri-Aqua
    1gfz
    No-Doz
    Ultra Pep-Back
    No Doz
    1-methyl-Theobromine
    Propoxyphene Compound-65
    Propoxyphene Compound 65
    CHEMBL113
    Berlin-Chemie Brand of Caffeine
    Pierre Fabre Brand of Caffeine
    2a3b
    Seid Brand of Caffeine
    1l7x
    1l5q
    Refresh'n
    Republic Drug Brand of Caffeine
    Bristol-Myers Squibb Brand of Caffeine
    Caffeine 99%
    AC1L1DV2
    Compound 65
    1,7-Trimethylxanthine
    Merck dura Brand of Caffeine
    Caffeina [Italian]
    Darvon compound-65
    PubChem9436
    Caffeine (natural)
    Theophylline, 7-methyl
    SureCN5671
    Koffein [German]
    O926
    Coffein [German]
    AC1Q3Z23
    HSDB 36
    nchembio774-comp2
    Anhydrous caffeine (TN)
    Caffeine (USP)
    NSC5036
    Kofein [Czech]
    SK-65 Compound
    Thompson Brand 2 of Caffeine
    SK 65 Compound
    ARONIS25359
    Thompson Brand 1 of Caffeine
    CID2519
    P-A-C Analgesic Tablets
    nchembio.63-comp5
    HMDB01847
    CTK1G9501
    Xanthine,3,7-trimethyl
    C2042
    W1139
    HMS502E12
    N1379
    C6035_SIGMA
    TNP00310
    Caffeine [BAN:JAN]
    DB00201
    C6035_FLUKA
    LP00228
    BIDD:PXR0172
    BIDD:GT0632
    BIDD:ER0554
    LS-237
    1,3,7-Trimethylxanthine
    C1778_SIAL
    C0750_SIAL
    bmse000206
    HMS2091O11
    HMS3260N17
    HMS1920I09
    SPECTRUM1500155
    1-3-7-TRIMETHYLXANTHINE
    D00528
    HMS2232M13
    CCRIS 1314
    C8960_SIAL
    C07481
    Theobromine, 1-methyl-
    C7731_SIAL
    nchembio.243-comp7
    DSSTox_CID_232
    ST057528
    STK177283
    NSC-5036
    DAP000099
    NSC 5036
    Anhydrous caffeine (JP15)
    Bio-0579
    BBL016491
    SBB006474
    Anhydrous caffeine (JP16)
    NSC755917
    C 0750
    NCI-C02733
    L000155
    75035_FLUKA
    W222402_ALDRICH
    CHEBI:27732
    27602_FLUKA
    UNII-3G6A5W338E
    D002110
    Spectrum_001301
    KBioSS_001781
    KBioGR_002325
    DSSTox_GSID_20232
    CCG-38825
    BSPBio_001921
    AC-12774
    Lopac-C-0750
    MolMap_000054
    Spectrum5_000423
    Spectrum4_001782
    NINDS_000730
    DSSTox_RID_75448
    Spectrum3_000321
    SPBio_001222
    Spectrum2_001261
    ZINC00001084
    A.S.A. and Codeine Compound
    AI3-20154
    NSC-755917
    Probes2_000128
    Probes1_000150
    NCIOpen2_008255
    Lopac0_000228
    KBio2_006917
    KBio2_004349
    PDSP2_001219
    I14-4386
    KBio2_001781
    PDSP2_001000
    MEGxp0_001350
    KBio1_000730
    PDSP1_001235
    AKOS000121334
    PDSP1_001016
    KBio3_001141
    DivK1c_000730
    ACon1_000085
    BRN 0017705
    MLS001055341
    Bio1_000473
    EU-0100228
    SMR000326667
    MLS001066409
    Bio1_001451
    IDI1_000730
    MLS001056714
    FEMA No. 2224
    Bio1_000962
    58-08-2
    1,7-Trimethyl-2,6-dioxopurine
    I14-19223
    Xanthine, 1,3,7-trimethyl
    Tox21_300010
    Tox21_201685
    CAS-58-08-2
    NCGC00090699-05
    NCGC00015208-03
    NCGC00015208-10
    NCGC00168808-01
    NCGC00015208-16
    NCGC00015208-04
    NCGC00090699-04
    NCGC00090699-09
    NCGC00015208-08
    NCGC00015208-15
    NCGC00015208-02
    NCGC00259234-01
    NCGC00090699-03
    NCGC00090699-08
    NCGC00015208-07
    NCGC00015208-13
    NCGC00015208-01
    NCGC00254057-01
    NCGC00090699-02
    NCGC00090699-07
    NCGC00015208-06
    NCGC00015208-12
    NCGC00015208-18
    NCGC00090699-01
    NCGC00090699-06
    NCGC00015208-05
    NCGC00015208-11
    NCGC00168808-02
    NCGC00015208-17
    NCGC00015208-14
    EINECS 200-362-1
    1,3,7-Trimethyl-2,6-dioxopurine
    Mettler-Toledo(R) Calibration substance ME 18872, Caffeine
    SDCCGMLS-0064595.P001
    Pharmakon1600-01500155
    95789-13-2
    71701-02-5
    1,3,7-Trimethylpurine-2,6-dione
    SDCCGMLS-0064595.P002
    3378-EP2305677A1
    3378-EP2311829A1
    3378-EP2277848A1
    3378-EP2305698A2
    3378-EP2316457A1
    3378-EP2295409A1
    3378-EP2308879A1
    3378-EP2316828A1
    3378-EP2305671A1
    3378-EP2311808A1
    3378-EP2275420A1
    3378-EP2305697A2
    3378-EP2314593A1
    3378-EP2289510A1
    3378-EP2308870A2
    3378-EP2316827A1
    3378-EP2305662A1
    3378-EP2311806A2
    3378-EP2269610A2
    3378-EP2305696A2
    3378-EP2314590A1
    3378-EP2284160A1
    3378-EP2308867A2
    3378-EP2316826A1
    3378-EP2305219A1
    3378-EP2311803A1
    3378-EP2305695A2
    3378-EP2314588A1
    3378-EP2280003A2
    3378-EP2308840A1
    3378-EP2316825A1
    3378-EP2301937A1
    3378-EP2311802A1
    3378-EP2305682A1
    3378-EP2311842A2
    MolPort-000-730-850
    3378-EP2277867A2
    3378-EP2308562A2
    3378-EP2316458A1
    3378-EP2295434A2
    3378-EP2311801A1
    3378-EP2371814A1
    BIM-0050216.0001
    CU-01000012617-3
    3,7-dihydro-1,3,7-trimethyl-1H-purine
    3,3,7-trimethyl-1H-purine-2,6-dione
    WLN: T56 BN DN FNVNVJ B1 F1 H1
    5-26-13-00558 (Beilstein Handbook Reference)
    5-26-13-00558 (Beilstein)
    1,3,7-trimethyl-1,3,7-trihydropurine-2,6-dione
    BRD-K02404261-001-03-5
    BRD-K02404261-001-02-7
    3,7-dihydro-1,3,7-trimethyl-1H-purine (9CI)
    3,7-Dihydro-1,3,7-trimethyl-1H-purine-2,6-dione
    1,3,7-Trimethyl-3,7-dihydro-1H-purine-2,6-dione
    3,7-Dihydro-1,3,7-trimethyl-1H-purin-2,6-dion
    1,3,7-trimethyl-2,6-dioxo-1,2,3,6-tetrahydropurine
    1H-Purine-2, 3,7-dihydro-1,3,7-trimethyl-
    1,3,7-trimethyl-1H-purine-2,6(3H,7H)-dione
    1H-Purine-2,6-dione, 3,7-dihydro-1,3,7-trimethyl-
    3,7-Dihydro-1,3,7-trimethyl-1H-purin-2,6-dion (coffein)
    2,6-Dioxo-2,3,6,7-tetrahydro-1,3,7-trimethyl-1H-purine
    1,3,7-trimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione
    07E4FB58-FD79-4175-8E3D-05BF96954522
    InChI=1/C8H10N4O2/c1-10-4-9-6-5(10)7(13)12(3)8(14)11(6)2/h4H,1-3H
    SmilesCN1C=NC2=C1C(=O)N(C(=O)N2C)C
    2519 
     
    FormulaC8H10N4O2
    Molweight194.191
    Heavy Atoms14
    Rotatable Bonds0
    H-bond donors0
    H-bond Acceptors 3
    Cluster numberNo cluster with more than 3 Compounds available
    Vendors
    ABI Chem
    AK Scientific, Inc. (AKSCI)
    AKos Consulting & Solutions
    Alsachim
    Ambinter
    ApexBio Technology
    Aronis
    Calbiochem
    CAPOT
    Chembase.cn
    ChemBridge
    ChemExper Chemical Directory
    ChemFrog
    ChemMol
    Hangzhou APIChem Technology
    IS Chemical Technology
    MP Biomedicals
    Sigma-Aldrich
    TCI (Tokyo Chemical Industry)
    TimTec
    Vitas-M Laboratory
    ZINC


    Chlorpromazine Phenolphthalinate


    Show similar structuresShow docking results

    Inhibition of:
    hERG: 1470 nM (ic50)
     5830 nM (ic50)
    TREK: 2700 nM (ic50)
    Metabolism
    Extrarenal fraction (Q0)Elimination half-life (EHL)
    130h
    Synonymous names
    Chlorpromazine phenolphthalinate
    Phenothiazine hydrochloride
    Largactilothiazine
    Prazilpromactil
    Chloropromazine
    chlorpromazine
    Chlorpromazine hibenzate
    Chlorpromazinum
    Thorazine Suppositories
    Thorazine hydrochloride
    Chlorpromazine Tannate
    Chlorderazin
    Clorpromazina
    Chlorpromados
    Chlorpromazin
    Chlordelazine
    Cromedazine
    Plegomazin
    Ampliactil
    Plegomasine
    Novo-Chlorpromazine
    Amplicitil
    Propaphenin
    Psychozine
    Novomazina
    Aminazine
    Largactyl
    Promazil
    Largactil
    Fenaktyl
    Amplictil
    Promapar
    Promactil
    Sonazine
    Propaphen
    Megaphen
    Aminazin
    Phenathyl
    Torazina
    Wintermin
    Thorazine
    Fenactil
    Phenactyl
    Thorazine Spansule
    Sanopron
    Contomin
    Aminasine
    Largactil Liquid
    Prozil
    Elmarin
    Esmind
    Chlor-Promanyl
    Proma
    Fraction AB
    2-Chloropromazine
    Largactil Oral Drops
    Chlorpromanyl (discontinued)
    CHEMBL71
    AC1L1EBT
    Chlor-PZ
    Clorpromazina [Italian]
    Z80
    SureCN8321
    Clorpromazina [INN-Spanish]
    Chlorpromazinum [INN-Latin]
    M176
    Chlorpromazine (USP/INN)
    UNII-U42B7VYA4P
    Thorazine (TN)
    CID2726
    C17H19ClN2S
    QSPL 401
    2601A
    JHICC02042
    Chlorpromazine [USAN:INN:BAN]
    CTK1C5154
    HMS501P06
    Chlorpromazine [USP:INN:BAN]
    BC 135
    NSC17479
    DB00477
    4560 Rp hydrochloride
    GG 407
    N-(3-Dimethylaminopropyl)-3-chlorophenothiazine
    SPECTRUM1500184
    SKF 2601A
    CCRIS 3711
    HMS2091E06
    HMS2089C12
    D00270
    HMS1920M03
    CHEBI:3647
    C06906
    HSDB 3033
    HL 5746
    NSC167745
    AK116446
    NSC756689
    STK182870
    DAP000374
    SKF-2601
    DSSTox_CID_2808
    L000182
    Spectrum_000142
    M-1209
    BSPBio_002011
    CCG-40059
    Lopac-C-8138
    BSPBio_000247
    STOCK1S-46588
    KBioSS_002314
    KBioSS_000622
    10-(3-Dimethylaminopropyl)-2-chlorophenothiazine
    KBioGR_002312
    DSSTox_GSID_22808
    KBioGR_000806
    SKF 2601-A
    Spectrum2_001156
    SPBio_002168
    Prestwick3_000064
    SPBio_001111
    Prestwick2_000064
    NINDS_000624
    Spectrum5_000717
    Prestwick1_000064
    cMAP_000017
    Spectrum4_000283
    Prestwick0_000064
    Spectrum3_000346
    DSSTox_RID_76736
    NSC 167745
    AB00051943
    NSC-167745
    4560 R.P
    LS-105361
    2-Cloro-10 (3-dimetilaminopropil)fenotiazina
    NSC-756689
    DivK1c_000624
    KBio2_003190
    KBio3_002792
    KBio2_002312
    KBio3_001231
    Oprea1_110255
    BPBio1_001181
    KBio2_000622
    Biomol-NT_000020
    KBio2_007448
    Lopac0_000249
    BPBio1_000273
    AKOS001490972
    KBio1_000624
    KBio2_005758
    I14-6226
    KBio2_004880
    Bio1_000946
    Bio1_000457
    AG-L-65223
    MLS003166901
    QTL1_000021
    Bio1_001435
    IDI1_000624
    SMR001453710
    50-53-3
    BAS 00010434
    Tox21_110120
    4560 R.P.
    CAS-69-09-0
    Chloro-3 (dimethylamino-3 propyl)-10 phenothiazine
    2-Chloro-10-[3-(dimethylamino)propyl]phenothiazine
    2-Chloro-10-(3-(dimethylamino)propyl)phenothiazine
    CAS-50-53-3
    NCGC00024409-07
    NCGC00015273-07
    NCGC00015273-13
    NCGC00015273-03
    NCGC00024409-06
    NCGC00015273-06
    NCGC00015273-12
    NCGC00015273-02
    NCGC00024409-05
    NCGC00015273-05
    NCGC00015273-10
    NCGC00015273-01
    NCGC00015273-17
    NCGC00024409-04
    NCGC00015273-04
    NCGC00015273-09
    NCGC00015273-16
    NCGC00015273-14
    NCGC00024409-08
    NCGC00015273-08
    NCGC00015273-15
    2-chloro-N,N-dimethyl-10H-Phenothiazine-10-propanamine
    NCGC00015273-11
    EINECS 200-045-8
    34468-21-8
    2-Cloro-10 (3-dimetilaminopropil)fenotiazina [Italian]
    Pharmakon1600-01500184
    2-chloro-10-(3-(dimethylamino)propyl)-phenothiazine
    MolPort-001-727-953
    Chloro-3 (dimethylamino-3 propyl)-10 phenothiazine [French]
    10H-Phenothiazine-10-propanamine, 2-chloro-N,N-dimethyl-
    SR-01000000012-5
    2-chloro-10-[3-(dimethylamino)propyl]-
    WLN: T C666 BN ISJ B3N1&1 EG
    Phenothiazine, 2-chloro-10-[3-(dimethylamino)propyl]-
    Phenothiazine, 2-chloro-10-(3-(dimethylamino)propyl)-
    3-(2-chlorophenothiazin-10-yl)-N,N-dimethylpropan-1-amine
    [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine
    3-(2-chlorophenothiazin-10-yl)-N,N-dimethyl-propan-1-amine
    3-(2-Chloro-10H-phenothiazin-10-yl)-N,N-dimethyl-1-propanamine
    3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine
    10H-Phenothiazine-10-propanamine, 2-chloro-N,N-dimethyl-, radical ion(1+)
    10-(3-Dimethylaminopropyl)-2-chlorophenothiazine; 3-(2-Chloro-10H-phenothiazin-10-yl)-N,N-dimethyl-1-propanamine
    SmilesCN(C)CCCN1C2=CC=CC=C2SC3=C1C=C(C=C3)Cl
    2726 
     
    12190308, 12873512,
    FormulaC17H19ClN2S
    Molweight318.864
    Heavy Atoms21
    Rotatable Bonds4
    H-bond donors0
    H-bond Acceptors 3
    Cluster numberNo cluster with more than 3 Compounds available
    Vendors
    ABI Chem
    AK Scientific, Inc. (AKSCI)
    AKos Consulting & Solutions
    Ambinter
    Angene Chemical
    Ark Pharm, Inc.
    ASINEX
    Aurum Pharmatech LLC
    Chembase.cn
    ChemFrog
    ChemMol
    IS Chemical Technology
    Vitas-M Laboratory


    Hydroxamates



    Inhibition of:
    TREK: 187 nM (ic50)
    Synonymous names
    Penfluridolum
    Hydroxamates
    PENFLURIDOL
    Micefal
    Semap
    AC1Q4JI6
    AC1L1PZ2
    Penfluridolum [INN-Latin]
    Penfluridol (USAN/INN)
    CHEMBL47050
    PubChem15873
    C28H27ClF5NO
    CTK8E9221
    TLP-607
    Semap (TN)
    D02630
    HMS3264L13
    UNII-25TLU22Q8H
    Penfluridol [USAN:BAN:INN]
    NSC759179
    DNC001108
    DNC000751
    L001145
    A818637
    AC-15413
    DSSTox_GSID_49021
    BCP9000014
    AK-73104
    DSSTox_CID_28947
    R 16341
    R-16341
    CHEBI:166843
    DSSTox_RID_83212
    ST51053793
    NSC-759179
    LS-116932
    PDSP2_000468
    PDSP1_000470
    mcn-jr 16341
    AKOS005065828
    AG-E-85053
    BRN 1558826
    R 16,341
    Tox21_113546
    BCP0726000159
    McN-JR-16,341
    NCGC00165865-01
    EINECS 248-074-5
    Pharmakon1600-01505691
    26864-56-2
    CAS-26864-56-2
    5-21-02-00409 (Beilstein Handbook Reference)
    1-[4,4-Bis(4-fluorophenyl)butyl]-4-[4-chloro-3(trifluoromethyl)phenyl]-4-piperidinol
    1-[4,4-bis(4-fluorophenyl)butyl]-4-[4-chloranyl-3-(trifluoromethyl)phenyl]piperidin-4-ol
    1-(4,4-Bis(p-fluorophenyl)butyl)-4-(4-chloro-alpha,alpha,alpha-trifluoro-m-tolyl)-4-piperidinol
    1-[4,4-Bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]-4-piperidinol
    1-(4,4-bis(4-fluorophenyl)butyl)-4-(4-chloro-3-(trifluoromethyl)phenyl)piperidin-4-ol
    1-[4,4-bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]piperidin-4-ol
    4-Piperidinol, 4-(4-chloro-alpha,alpha,alpha-trifluoro-m-tolyl)-1-(4,4-bis(p-fluorophenyl)butyl)-
    4-Piperidinol, 1-(4,4-bis(p-fluorophenyl)butyl)-4-(4-chloro-alpha,alpha,alpha-trifluoro-m-tolyl)-
    4-Piperidinol, 1-(4,4-bis(4-fluorophenyl)butyl)-4-(4-chloro-3-(trifluoromethyl)phenyl)-
    4-Piperidinol, 1-[4,4-bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]-
    4-Piperidinol,1-[4,4-bis(p-fluorophenyl)butyl]-4-(4-chloro-a,a,a-trifluoro-m-tolyl)- (8CI);1-[4,4-Bis(p-fluorophenyl)butyl]-4-(4-chloro-a,a,a-trifluoro-m-tolyl)-4-piperidinol;McN-JR 16341;Penfluridol;
    SmilesC1CN(CCC1(C2=CC(=C(C=C2)Cl)C(F)(F)F)O)CCCC(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F
    33630 
     
    FormulaC28H27ClF5NO
    Molweight523.965
    Heavy Atoms36
    Rotatable Bonds7
    H-bond donors1
    H-bond Acceptors 7
    Cluster numberNo cluster with more than 3 Compounds available
    Vendors
    ABI Chem
    AK Scientific, Inc. (AKSCI)
    AKos Consulting & Solutions
    Amadis Chemical
    Ambinter
    Angene Chemical
    Ark Pharm, Inc.
    BioChemPartner
    CAPOT
    Chembase.cn
    ChemFrog
    ChemMol
    Hangzhou APIChem Technology
    Oakwood Products


    Triflumethazine



    Inhibition of:
    TREK: 4700 nM (ic50)
    Metabolism
    Extrarenal fraction (Q0)Elimination half-life (EHL)
    130h
    Synonymous names
    Triflumethazine
    Phthorphenazine
    Fluorphenazine
    Fluorophenazine
    FLUPHENAZINE
    Ftorphenazine
    Fluphenazinum
    Fluorfenazine
    Permitil Concentrate
    Flufenazin
    Calmansial
    Flufenazina
    Prolixin Concentrate
    Vespazine
    Permitil
    Yespazine
    Siqualon
    Anatensol
    Prolixine
    Siqualine
    Hydrochloride, Fluphenazine
    Prolixin
    Pacinol
    Dapotum
    FLUPHENAZINE HCL
    Sevinol
    Apo-Fluphenazine
    Elinol
    Moditen Hcl
    AC1L1FSB
    CHEMBL726
    S94
    Fluphenazine (INN)
    Flufenazina [DCIT]
    Fluphenazinum [INN-Latin]
    CID3372
    Fluphenazine [INN:BAN]
    SureCN19221
    HMS655L02
    Moditen (TN)
    CTK8F9822
    nchembio873-comp68
    BIDD:PXR0184
    C22H26F3N3OS
    NSC62323
    DB00623
    HMS2089C16
    HSDB 3334
    D07977
    CHEBI:5123
    C07010
    Moditen (Tabl or elixir)
    AK116209
    DAP000375
    Bio-0775
    SQ 4918
    STK050763
    GSK163090
    DCL000806
    DCL000371
    D005476
    L000257
    A 4077
    DSSTox_CID_3068
    A836405
    Spectrum_000289
    KBioGR_002386
    KBioGR_001375
    NSC 62323
    BSPBio_003100
    Lopac-F-4765
    KBioSS_002391
    BSPBio_000320
    KBioSS_000769
    DSSTox_GSID_23068
    Prestwick2_000320
    Spectrum5_001536
    Prestwick1_000320
    Spectrum4_000828
    DSSTox_RID_76862
    Prestwick0_000320
    NINDS_000511
    Spectrum3_001420
    cMAP_000035
    Spectrum2_001199
    SPBio_002539
    CHEBI:136842
    Prestwick3_000320
    SPBio_001277
    CCG-204645
    ChemDiv1_024180
    Probes2_000295
    AB00053587
    Probes1_000254
    UNII-S79426A41Z
    LS-112565
    KBio2_002386
    Biomol-NT_000023
    DivK1c_000511
    KBio3_002320
    BPBio1_001187
    KBio2_000769
    KBio2_007522
    Lopac0_000555
    BPBio1_000352
    KBio1_000511
    KBio2_005905
    KBio2_004954
    KBio2_003337
    KBio3_002865
    AKOS001659031
    AG-G-69216
    IDI1_000511
    AG-H-13390
    69-23-8
    Tox21_110146
    CAS-69-23-8
    NCGC00015436-03
    NCGC00015436-02
    NCGC00024429-04
    NCGC00015436-09
    NCGC00015436-01
    NCGC00024429-03
    NCGC00015436-06
    NCGC00015436-08
    NCGC00015436-05
    NCGC00015436-07
    NCGC00015436-04
    CAS-146-56-5
    EINECS 200-702-9
    47646-09-3
    78126-11-1
    10-(3-(2-Hydroxyethyl)piperazinopropyl)-2-(trifluoromethyl)phenothiazine
    MolPort-001-727-938
    1451-EP2298776A1
    1451-EP2272537A2
    SR-01000003048-5
    4-(3-(-Trifluoromethyl-10-phenothiazyl)-propyl)-1-piperazineethanol
    4-[3-(2-Trifluoromethyl-10-phenothiazyl)-propyl]-1-piperazineethanol
    4-(3-(2-Trifluoromethyl-10-phenothiazyl)-propyl)-1-piperazineethanol
    1-(2-Hydroxyethyl)-4-[3-(trifluoromethyl-10-phenothiazinyl)propyl]piperazine
    4-(3-(2-(trifluoromethyl)phenothiazin-10-yl)propyl)-1-Piperazineethanol
    1-(2-Hydroxyethyl)-4-(3-(trifluoromethyl-10-phenothiazinyl)propyl)-piperazine
    BRD-K55127134-300-05-4
    BRD-K55127134-001-01-7
    1-Piperazineethanol, 4-(3-(2-(trifluoromethyl)phenothiazin-10-yl)propyl)-
    2-(Trifluoromethyl)-10-(3-(1-(beta-hydroxyethyl)-4-piperazinyl)propyl)phenothiazine
    2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethanol dihydrochloride
    4-(3-(2-(Trifluoromethyl)-10H-phenothiazin-10-yl)propyl)-1-piperazineethanol
    2-(Trifluoromethyl)-10-(3-(1-(beta-hydroxyethyl)-4-pipe razinyl)propyl)phenothiazine
    10-(3'-(4"-(beta-Hydroxyethyl)-1"-piperazinyl)-propyl)-3-trifluoromethylphenothiazine
    2-[4-[3-[2-(trifluoromethyl)-10-phenothiazinyl]propyl]-1-piperazinyl]ethanol
    2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethanol
    1-Piperazineethanol, 4-(3-(2-(trifluoromethyl)-10H-phenothiazin-10-yl)propyl)-
    1-Piperazineethanol, 4-[3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl]-
    Phenothiazine, 10-(3-(4-(2-hydroxyethyl)-1-piperazinyl)propyl)-2-(trifluoromethyl)-
    2-(4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}piperazin-1-yl)ethanol
    2-(4-(3-(2-(trifluoromethyl)-10H-phenothiazin-10-yl)propyl)piperazin-1-yl)ethanol
    2-(4-(3-[2-(Trifluoromethyl)-10H-phenothiazin-10-yl]propyl)-1-piperazinyl)ethanol
    1-Piperazineethanol, 4-(3-(2-(trifluoromethyl)-10H-phenothiazin-10-yl)propyl)- (9CI)
    10-(3'-(4''-(beta-Hydroxyethyl)-1''-piperazinyl)-propyl)-3-trifluoromethylphenothiazine
    1-Piperazineethanol,4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]- (6CI,7CI,8CI);1-(2-Hydroxyethyl)-4-[3-(trifluoromethyl-10-phenothiazinyl)propyl]piperazine;10-[3-(2-Hydroxyethyl)piperazinoprop
    SmilesC1CN(CCN1CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)C(F)(F)F)CCO
    3372 
     
    FormulaC22H26F3N3OS
    Molweight437.522
    Heavy Atoms30
    Rotatable Bonds6
    H-bond donors1
    H-bond Acceptors 8
    Cluster numberNo cluster with more than 3 Compounds available
    Vendors
    ABI Chem
    AKos Consulting & Solutions
    Amadis Chemical
    Ambinter
    Angene Chemical
    Angene International
    Ark Pharm, Inc.
    Chembase.cn
    ChemFrog
    Vitas-M Laboratory


    Fluoxetine


    Show similar structuresShow docking results

    Inhibition of:
    hERG: 3100 nM (ic50)
     5820 nM (ic50)
    TREK: 19000 nM (ic50)
    Metabolism
    Extrarenal fraction (Q0)Elimination half-life (EHL)
    0.8548h
    Synonymous names
    Fluoxetina
    fluoxetine
    Fluoxetinum
    Reconcile
    Floxetine
    Reneuron
    Pulvules
    Fluoxetin
    Fluoxeren
    Portal
    Foxetin
    Adofen
    Fontex
    Fluval
    Prozac Weekly
    Eufor
    Fluoxetine Hcl
    Animex-On
    CHEMBL41
    AC1L1FTH
    Prozac, among others
    fluoxetine (Prozac)
    Fluoxetina [Spanish]
    SureCN8353
    BEN445
    Fluoxetina [INN-Spanish]
    Fluoxetine (TN)
    Fluoxetinum [INN-Latin]
    CID3386
    N-Methyl-gamma-(4-(trifluoromethyl)phenoxy)benzenepropanamine
    CTK8D4092
    C17H18F3NO
    Fluoxetine (USAN/INN)
    DB00472
    D00326
    CHEBI:5118
    Fluoxetine [USAN:INN:BAN]
    UNII-01K63SUP8D
    HMS2090H14
    nchembio.534-comp2
    DAP000186
    ST076807
    STK734483
    BBL012251
    NSC283480
    Bio-0787
    SBB017267
    SpecPlus_000723
    DSSTox_CID_3067
    L000931
    Spectrum_001679
    KBioGR_001166
    DSSTox_GSID_23067
    BSPBio_003375
    BSPBio_000461
    LS-31040
    N-Methyl-3-(p-trifluoromethylphenoxy)-3-phenylpropylamine
    AC-14564
    3-(p-Trifluoromethylphenoxy)-N-methyl-3-phenylpropylamine
    KBioSS_002159
    TL8003595
    Spectrum2_001658
    SPBio_002382
    Prestwick3_000511
    SPBio_001815
    DSSTox_RID_76861
    Prestwick2_000511
    Spectrum5_001518
    Prestwick1_000511
    Spectrum4_000613
    Prestwick0_000511
    Lilly-110140
    Spectrum3_001648
    NSC-283480
    CCG-204648
    AB00053774
    AKOS003663021
    KBio1_001763
    Biomol-NT_000152
    dl-3-(p-Trifluoromethylphenoxy)-N-methyl-3-phenylpropylamine
    KBio3_002595
    BPBio1_000509
    KBio2_007295
    DivK1c_006819
    BPBio1_000354
    KBio2_004727
    Lopac0_000558
    KBio2_002159
    AG-F-91570
    Tox21_110144
    (+/-)-Fluoxetine
    benzenepropanamine, N-methyl-gamma-[4-(trifluoromethyl)phenoxy]-
    NCGC00024879-03
    NCGC00015428-06
    NCGC00015428-10
    NCGC00015428-13
    NCGC00015428-08
    NCGC00015428-12
    NCGC00015428-11
    Benzenepropanamine, N-methyl-|A-[4-(trifluoromethyl)phenoxy]-
    NCGC00024879-04
    NCGC00015428-07
    57226-07-0
    methyl{3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl}amine
    52341-67-0
    54910-89-3
    100568-03-4
    MolPort-001-683-482
    CAS-54910-89-3
    (+-)-N-Methyl-gamma-(4-(trifluoromethyl)phenoxy)benzenepropanamine
    Benzenepropanamine, N-methyl-.gamma.-[4-(trifluoromethyl)phenoxy]-
    59333-67-4 (hydrochloride)
    Methyl-[3-phenyl-3-(4-trifluoromethyl-phenoxy)-propyl]-amine
    Methyl({3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl})amine
    (+/-)-N-Methyl-gamma-[4-(trifluoromethyl)phenoxy]benzenepropanamine
    N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine
    (+/-)-N-Methyl-3-(p-trifluoromethylphenoxy)-3-phenylpropylamine
    (+/-)-N-Methyl-3-p-(p-trifluoromethylphenoxy)-3-phenylpropylamine
    N-methyl-3-phenyl-3-{[4-(trifluoromethyl)phenyl]oxy}propan-1-amine
    BRD-A31159102-003-05-6
    BRD-A31159102-001-01-9
    (+) or (-)-N-Methyl-gamma-(4-(trifluoromethyl)phenoxy)benzenepropanamine
    Benzenepropanamine, N-methyl-gamma-(4-(trifluoromethyl)phenoxy)-, (+-)-
    Benzenepropamine, N-methyl-gamma-(4-(trifluoromethyl)phenoxy)-, (+-)-
    (+/-)-N-Methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propylamine]
    (+-)-N-Methyl-3-phenyl-3-((alpha,alpha,alpha-trifluoro-p-tolyl)oxy)propylamine
    Benzenepropanamine, N-methyl-gamma-[4-(trifluoromethyl)phenoxy]-, (+/-)-
    (+/-)-N-Methyl-3-phenyl-3-[(alpha,alpha,alpha-trifluoro-p-tolyl)oxy]propylamine
    (+) or (-)-N-Methyl-3-phenyl-3-((alpha,alpha,alpha-trifluoro-p-tolyl)oxy)propylamine
    Benzenepropanamine, N-methyl-.gamma.-[4-(trifluoromethyl)phenoxy]-, (.+/-.)-
    Fluoxetine (TN);Fluoxetine (USAN);(+/-)-N-Methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propylamine];Prozac;dl-3-(p-Trifluoromethylphenoxy)-N-methyl-3-phenylpropylamine;Pulvules;Fluval;3-(p-Trifluorom
    SmilesCNCCC(C1=CC=CC=C1)OC2=CC=C(C=C2)C(F)(F)F
    3386 
     
    12873512, 20637635,
    FormulaC17H18F3NO
    Molweight309.326
    Heavy Atoms22
    Rotatable Bonds6
    H-bond donors1
    H-bond Acceptors 5
    Cluster numberCluster1083
    Vendors
    Abbott Labs
    ABI Chem
    AKos Consulting & Solutions
    Alsachim
    Ambinter
    Angene Chemical
    Chembase.cn
    ChemExper Chemical Directory
    ChemFrog
    ChemMol
    Fragmenta
    Hangzhou APIChem Technology
    Hangzhou Trylead Chemical Technology
    TimTec
    Vitas-M Laboratory


    Spirodiflamine


    Show similar structuresShow docking results

    Inhibition of:
    hERG: 2300 nM (ic50)
    TREK: 232 nM (ic50)
    Synonymous names
    Spirodiflamine
    Fluspirilenum
    Fluspirileno
    Fluspirilene
    Fluspirilen
    Redeptin
    Imap
    AC1L1FUB
    spiropiperidine analogue, 1
    UNII-C5QA4GLR9M
    Fluspirileno [INN-Spanish]
    Fluspirilenum [INN-Latin]
    Fluspirilene (USAN/INN)
    SureCN42082
    CHEMBL46516
    F100_SIGMA
    CID3396
    R6218
    CTK7B9885
    Fluspirilene [USAN:INN:BAN]
    Imap (TN)
    DB04842
    HMS2089C15
    HMS1989D05
    HMS1791D05
    D02629
    HMS3261H17
    HMS1570F14
    HMS2233B20
    C29H31F2N3O
    F-100
    HMS2097F14
    DAP000980
    Bio-0707
    Lopac-F-100
    R 6218
    L001195
    DSSTox_GSID_45152
    BSPBio_001343
    BSPBio_000752
    Prestwick0_000906
    Prestwick3_000906
    DSSTox_RID_80706
    Prestwick2_000906
    McN-JR-6218
    DSSTox_CID_25152
    Prestwick1_000906
    SPBio_002951
    AB00513956
    LS-154759
    CCG-204608
    AKOS015969747
    Oprea1_804941
    Lopac0_000518
    BPBio1_000828
    EU-0100518
    MLS001333730
    BRN 0633853
    SMR000058304
    AG-K-47958
    MLS000069357
    AG-E-33706
    Tox21_110142
    NCGC00093913-04
    NCGC00015424-05
    NCGC00015424-04
    1841-19-6
    NCGC00093913-03
    NCGC00015424-03
    NCGC00015424-02
    NCGC00093913-02
    NCGC00015424-01
    NCGC00015424-09
    NCGC00093913-01
    NCGC00015424-07
    NCGC00016595-01
    NCGC00093913-05
    NCGC00015424-06
    NCGC00015424-08
    EINECS 217-418-6
    CAS-1841-19-6
    MolPort-002-540-769
    5-26-04-00097 (Beilstein Handbook Reference)
    BRD-K77947974-001-04-9
    1-Phenyl-4-oxo-8-(4,4-bis(4-fluorophenyl)butyl)-1,3,8-triazaspiro(4,5)decane
    8-[4,4-bis(p-Fluorophenyl)butyl]-1-phenyl-1,3,8-triazino[4.5]decan-4-one
    8-[4,4-bis(4-fluorophenyl)butyl]-4-phenyl-2,4,8-triazaspiro[4.5]decan-1-one
    8-[4,4-bis(4-fluorophenyl)butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
    8-(4,4-Bis(p-fluorophenyl)butyl)-1-phenyl-1,3,8-triazaspiro-(4.5)decan-4-one
    8-[4,4-bis (p-fluorophenyl)butyl]-1-phenyl-1,3,8-triazino[4,5]decan-4-one
    1,3,8-Triazaspiro(4.5)decan-4-one, 8-(4,4-bis(p-fluorophenyl)butyl)-1-phenyl-
    8-[4,4-bis (p-fluorophenyl)butyl]- 1-phenyl-1,3,8-triazino[4,5]decan-4-one
    1,3,8-Triazaspiro[4.5]decan-4-one, 8-[4,4-bis(4-fluorophenyl)butyl]-1-phenyl-
    1,3,8-Triazaspiro(4.5)decan-4-one, 8-(4,4-bis(4-fluorophenyl)butyl)-1-phenyl-
    1,3,8-Triazaspiro[4.5]decan-4-one,8-[4,4-bis(p-fluorophenyl)butyl]-1-phenyl- (7CI,8CI);8-[4,4-Bis(p-fluorophenyl)butyl]-1-phenyl-1,3,8-triazaspiro[4,5]decan-4-one;Fluspirilen; Fluspirilene; Fluspirili
    SmilesC1CN(CCC12C(=O)NCN2C3=CC=CC=C3)CCCC(C4=CC=C(C=C4)F)C5=CC=C(C=C5)F
    3396 
     
    15324906,
    FormulaC29H31F2N3O
    Molweight475.573
    Heavy Atoms35
    Rotatable Bonds7
    H-bond donors1
    H-bond Acceptors 5
    Cluster numberCluster359
    Vendors
    ABI Chem
    AKos Consulting & Solutions
    Ambinter
    Angene Chemical
    Chembase.cn
    MP Biomedicals
    Sigma-Aldrich


    Glybenzcyclamide


    Show similar structuresShow docking results

    Inhibition of:
    hERG: 74000 nM (ic50)
    TREK: 64000 nM (ic50)
    Metabolism
    Extrarenal fraction (Q0)Elimination half-life (EHL)
    13-10h
    Synonymous names
    Glybenzcyclamide
    Glibenclamidum
    Glibenclamid-Ratiopharm
    Praeciglucon
    Glibenclamida
    Glybenclamide
    Abbenclamide
    Glibenclamide
    Glibenclamid Genericon
    Glibenclamid Heumann
    Glibenbeta
    Normoglucon
    Glibenclamid-Cophar
    Gewaglucon
    Glycolande
    Lisaglucon
    Glibenclamid Basics
    Duraglucon
    Hexaglucon
    Bastiverit
    Diabiphage
    Glucoremed
    Micronized glyburide
    Neogluconin
    Glimidstata
    Glucohexal
    Glibetic
    Orabetic
    Glitisol
    Euglykon
    Glucoven
    Apo-Glibenclamide
    Micronase
    Glibesyn
    Miglucan
    Calabren
    Glisulin
    Yuglucon
    Euglucon
    Glucomid
    Betanase
    Euglucan
    Glucolon
    Glibadone
    Glibenil
    Lederglib
    Glibenclamid Fabra
    Benclamin
    Glidiabet
    Renabetic
    Euclamin
    Glucobene
    glyburide
    Azuglucon
    Gliboral
    Prodiabet
    Glycomin
    Glycron
    Diabeta
    Cytagon
    Glibil
    Maninil
    Glibet
    Glibens
    Libanil
    Glyben
    Glynase
    Glimide
    Suraben
    Gliben
    Gluben
    Daonil
    Tiabet
    Gliban
    Glibenclamid AL
    Glamide
    Humedia
    Glimel
    Sugril
    Dibelet
    Glubate
    Debtan
    Gilemal
    Glicem
    PresTab
    Nadib
    Adiab
    Novo-Glyburide
    Melix
    Semi-Euglucon
    Pira
    Gluco-Tablimen
    Glibenclamide;Glycron;Glynase;Micronase;Daonil;Semi-Daonil;Euglucon;Delmide;Diabeta
    Med-Glionil
    Hemi-Daonil
    Glibenclamid Riker M
    Semi-daonil
    Glyburide-Supplied by Selleck Chemicals
    Dia-basan
    Gen-Glybe
    Euglucon N
    Euglucon 5
    Gliben-Puren N
    Betanese 5
    Norglicem 5
    Glibenclamid Riker M.
    CHEMBL472
    Glyburide (micronized)
    Semi-Gliben-Puren N
    AC1L1G1Q
    Glibenclamidum [INN-Latin]
    UNII-SX6K58TVWC
    HB420
    HB419
    GBN 5
    Glibenclamida [INN-Spanish]
    Glyburide [USAN]
    UPCMLD-DP006
    Glyburide (USP)
    Prestwick_569
    AC1Q44V7
    Micronase (TN)
    SureCN22009
    CID3488
    G0382
    Glynase (TN)
    Diabeta (TN)
    S1716_Selleck
    HMS501I03
    CTK8B7917
    Glyburide [USAN:USP]
    HB-420
    DB01016
    HB 420
    Tocris-0911
    BIDD:GT0239
    ACMC-20a66i
    C23H28ClN3O5S
    UR 606
    HB 419
    G0639_SIGMA
    HB-419
    HMS3261D19
    HMS1791D13
    C07022
    HMS3259O12
    A19539
    G2539_SIAL
    HMS1568P14
    SPECTRUM2300229
    HMS2093P04
    HMS2095P14
    G0639_SIAL
    HMS1361D13
    CHEBI:5441
    HMS2089L06
    HMS1989D13
    HMS3267A15
    HMS1922L08
    D00336
    Glibenclamide (JP16/INN)
    Bio-0156
    Glibenclamide (JP15/INN)
    SBB057426
    STK362992
    NSC759618
    DAP000037
    ST024780
    Spectrum_000250
    G 0639
    D005905
    KBioGR_001897
    ANW-58936
    BCP9000729
    KBioGR_000071
    Lopac-G-0639
    BSPBio_003053
    DSSTox_GSID_37237
    AB2000243
    BSPBio_001351
    KBioSS_000730
    BSPBio_000312
    KBioSS_000071
    CCG-39618
    AK-56404
    DSSTox_CID_17237
    Prestwick0_000316
    Spectrum3_001327
    ZINC00537805
    U-26452
    Spectrum2_001816
    Prestwick3_000316
    SPBio_002531
    NINDS_000481
    Prestwick2_000316
    SPBio_001831
    Spectrum5_001631
    DSSTox_RID_79313
    Prestwick1_000316
    Spectrum4_001199
    CBiol_001790
    U 26452
    Probes2_000378
    Probes1_000431
    AB00051949
    NSC-759618
    LS-159295
    BPBio1_000344
    DivK1c_000481
    KBio2_000730
    Oprea1_764617
    KBio3_000141
    AKOS001487495
    KBio2_000071
    Lopac0_000499
    KBio2_005866
    KBio1_000481
    KBio2_005207
    I06-0716
    KBio2_003298
    KBio3_002273
    UPCMLD-DP006:001
    KBio2_002639
    KBio3_000142
    Bio1_001054
    SMR000058229
    Bio1_000565
    SAM002564212
    Bio1_000076
    CPD000058229
    EU-0100499
    Bio2_000551
    IDI1_033821
    BRN 2230085
    MLS001077262
    Bio2_000071
    IDI1_000481
    MLS000069721
    5-Chloro-N-[4-(cyclohexylureidosulfonyl)phenethyl]-2-methoxybenzamide
    U-26,452
    Tox21_300758
    Tox21_110158
    NCGC00015467-07
    NCGC00023447-10
    NCGC00015467-13
    NCGC00015467-06
    NCGC00254662-01
    NCGC00023447-04
    NCGC00015467-05
    NCGC00023447-09
    NCGC00015467-12
    NCGC00015467-02
    NCGC00015467-18
    NCGC00023447-02
    NCGC00015467-04
    NCGC00023447-08
    NCGC00015467-10
    NCGC00015467-01
    NCGC00015467-17
    NCGC00016689-01
    NCGC00015467-03
    NCGC00023447-07
    NCGC00015467-09
    NCGC00023447-12
    NCGC00015467-15
    NCGC00015467-16
    NCGC00023447-06
    NCGC00015467-08
    NCGC00023447-11
    NCGC00015467-14
    NCGC00015467-11
    NCGC00023447-05
    EINECS 233-570-6
    5-Chloro-N-[4-(3-cyclohexylureidosulfonyl)phenethyl]-2-methoxybenzamide
    Pharmakon1600-02300229
    10238-21-8
    CAS-10238-21-8
    MolPort-000-784-850
    5-Chloro-N-(4-(N-(cyclohexylcarbamoyl)sulfamoyl)phenethyl)-2-methoxybenzamide
    78637-EP2270001A1
    78637-EP2287165A2
    78637-EP2298779A1
    78637-EP2275414A1
    5-chloro-N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-2-methoxybenzamide
    78637-EP2298776A1
    78637-EP2308847A1
    78637-EP2272841A1
    78637-EP2298750A1
    78637-EP2305648A1
    78637-EP2272825A2
    78637-EP2292620A2
    78637-EP2301936A1
    78637-EP2270011A1
    78637-EP2287166A2
    78637-EP2301923A1
    Glibenclamide, Glycron, Glynase, Micronase, Daonil, Semi-Daonil, Euglucon, Delmide, Glyburide
    SR-01000000196-5
    N-p-[2-(5-Chloro-2-methoxybenzamido)ethyl]benzenesulfonyl-N'-cyclohexylurea
    5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide
    N-p-[2-(5-Chloro-2-methoxybenzamido)-ethyl]benzene-sulfonyl-N -cyclohexylurea
    1-(p-(2-(5-Chloro-2-methoxybenzamido)ethyl)benzenesulfonyl)-3-cyclohexylurea
    N-p-[2-(5-Chloro-2-methoxybenzamido)-ethyl]benzene-sulfonyl-N'-cyclohexylurea
    BRD-K36927236-001-06-0
    N-(4-(2-(5-Chloro-2-methoxybenzamido)ethyl)phenylsulfonyl)-N'-cyclohexylurea
    5-chloro-N-[2-(4-{[(cyclohexylcarbamoyl)amino]sulfonyl}phenyl)ethyl]-2-methoxybenzamide
    5-chloro-N-(2-{4-[N-(N-cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide
    N-[(4-{2-[(5-chloro-2-methoxyphenyl)carbonylamino]ethyl}phenyl)sulfonyl](cyclo hexylamino)carboxamide
    1-((p-(2-(5-Chloro-o-anisamido)ethyl)phenyl)sulfonyl)-3-cyclohexylurea
    N-(4-(beta-(2-Methoxy-5-chlorbenzamido)-aethyl)-benzolsulfonyl)-N'-cyclohexyl-harnstoff
    (5-chloro-2-methoxyphenyl)-N-[2-(4-{[(cyclohexylamino)carbonylamino]sulfonyl}p henyl)ethyl]carboxamide
    5-Chloro-N-(2-(4-((((cyclohexylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-2-methoxybenzamide
    Urea, 1-(p-(2-(5-chloro-2-methoxybenzamido)ethyl)benzenesulfonyl)-3-cyclohexyl-
    Urea, 1-((p-(2-(chloro-o-anisamido)ethyl)phenyl)sulfonyl)-3-cyclohexyl-
    Benzamide, 5-chloro-N-(2-(4-((((cyclohexylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-2-methoxy-
    Benzamide, 5-chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]-2-methoxy-
    Benzamide, 5-chloro-N-[2-[4-[[[(cyclohexylamino) carbonyl]amino]sulfonyl]phenyl]ethyl] -2-methoxy-
    SmilesCOC1=C(C=C(C=C1)Cl)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCCCC3
    3488 
     
    18243713, 12190308,
    FormulaC23H28ClN3O5S
    Molweight494.004
    Heavy Atoms33
    Rotatable Bonds8
    H-bond donors3
    H-bond Acceptors 5
    Cluster numberNo cluster with more than 3 Compounds available
    Vendors
    ABBLIS Chemicals
    Abbott Labs
    ABI Chem
    Achemica
    AK Scientific, Inc. (AKSCI)
    AKos Consulting & Solutions
    Amadis Chemical
    Ambinter
    Anward
    Ark Pharm, Inc.
    BioChemPartner
    Calbiochem
    Chembase.cn
    ChemExper Chemical Directory
    ChemFrog
    ChemMol
    IS Chemical Technology
    MP Biomedicals
    NIH Clinical Collection
    Selleck Chemicals
    Sigma-Aldrich
    TCI (Tokyo Chemical Industry)
    TimTec
    Vitas-M Laboratory


    Haloperidolum


    Show similar structuresShow docking results

    Inhibition of:
    hERG: 26.8 nM (ic50)
     28.10 nM (ic50)
     32 nM (ic50)
     230 nM (ic50)
     120 nM (ki)
    TREK: 5500 nM (ic50)
    Metabolism
    Extrarenal fraction (Q0)Elimination half-life (EHL)
    120h
    Synonymous names
    Haloperidolum
    Aloperidin
    Haloperidol Intensol
    Halopoidol
    Aloperidon
    Aloperidol
    Sigaperidol
    Galoperidol
    haloperidol
    Bioperidolo
    Aloperidolo
    Haloperido
    Serenace
    Uliolind
    Eukystol
    Fortunan
    LNEPOXFFQSENCJ-UHFFFAOYSA-
    Lealgin compositum
    Ulcolind
    Halosten
    Serenase
    Brotopon
    Halopidol
    Halojust
    Serenelfi
    Vesalium
    Sernas
    Halidol
    Keselan
    Peridol
    Pernox
    Pekuces
    Mixidol
    Pms Haloperidol
    Haldol
    Linton
    Apo-Haloperidol
    Halopal
    Sernel
    Peluces
    Halol
    Haloperidol-Supplied by Selleck Chemicals
    Haldol Solutab
    Aldo
    Dozic
    Dozix
    Aloperidin;Bioperidolo;Brotopon;Dozic;Duraperidol;Einalon S;Haldol
    Novo-Peridol
    Haldol La
    Einalon S
    CHEMBL54
    Aloperidolo [Italian]
    AC1L1G7K
    SureCN8264
    Aloperidolo [DCIT]
    Prestwick_250
    Haloperidolum [INN-Latin]
    AC1Q77Z0
    CID3559
    C21H23ClFNO2
    HMS502A16
    S1920_Selleck
    H0912
    W0039
    DB00502
    BIDD:GT0128
    Tocris-0931
    H1512_SIGMA
    HSDB 3093
    HMS2089M15
    HMS3261F08
    HMS1920D03
    HMS2234P08
    SPECTRUM1500325
    CHEBI:5613
    HMS1568G12
    HMS2095G12
    CCRIS 1630
    D00136
    Aloperidin, Bioperidolo, Brotopon, Dozic, Haloperidol
    HMS2091J09
    C01814
    DAP000313
    NSC615296
    Bio-0705
    NSC170973
    NSC757054
    R 1625
    UNII-J6292F8L3D
    D006220
    L000288
    H 1512
    Haloperidol (JP15/USP)
    Haloperidol [USAN:INN:BAN:JAN]
    R-1625
    Spectrum_000861
    KBioSS_001341
    AC-19691
    CCG-39111
    KBioGR_002390
    AB2000375
    CCG-36042
    KBioGR_000980
    DSSTox_GSID_34150
    Lopac-H-1512
    BSPBio_002096
    BSPBio_000130
    KBioSS_002395
    LS-48311
    Spectrum5_000788
    Prestwick1_000115
    Spectrum4_000570
    Prestwick0_000115
    Spectrum3_000448
    Spectrum2_001268
    SPBio_002069
    NINDS_000654
    Prestwick3_000115
    SPBio_001236
    DSSTox_RID_79117
    cMAP_000037
    McN-JR-1625
    Prestwick2_000115
    DSSTox_CID_14150
    ST50319916
    Haloperidol (JP15/USP/INN)
    Haloperidol [USAN:USP:INN:BAN:JAN]
    NSC 615296
    NSC-757054
    NSC 170973
    NSC-615296
    Probes2_000296
    NSC-170973
    Probes1_000255
    AB00052008
    Haloperidol (JP16/USP/INN)
    Oprea1_509923
    DivK1c_000654
    KBio2_004958
    Lopac0_000583
    BPBio1_001231
    KBio2_003909
    KBio3_002869
    BPBio1_000144
    KBio2_002390
    AKOS000280660
    KBio3_001316
    KBio2_001341
    KBio2_007526
    Biomol-NT_000035
    KBio1_000654
    KBio2_006477
    MLS000028450
    IDI1_000654
    BRN 0331267
    EU-0100583
    SMR000058303
    MLS001146904
    QTL1_000042
    I14-14165
    I14-13404
    52-86-8
    Tox21_300475
    Tox21_110162
    gamma-(4-(p-Chlorophenyl)-4-hydroxypiperidino)-p-fluorobutyrophenone
    VU0239704-10
    CAS-52-86-8
    gamma-(4-(p-Chlorophenyl)-4-hydroxypiperidino)-p-fluorbutyrophenone
    NCGC00015500-14
    NCGC00015500-16
    NCGC00023875-06
    NCGC00015500-08
    NCGC00015500-10
    NCGC00015500-15
    NCGC00023875-05
    NCGC00015500-07
    NCGC00015500-06
    NCGC00015500-13
    NCGC00023875-04
    NCGC00023875-09
    NCGC00015500-05
    NCGC00015500-02
    NCGC00015500-12
    NCGC00023875-02
    NCGC00254503-01
    NCGC00023875-08
    NCGC00015500-04
    NCGC00015500-01
    NCGC00015500-11
    gamma-(4-(p-Chlorophenyl)-4-hydroxpiperidino)-p-fluorbutyrophenone
    NCGC00016234-01
    NCGC00015500-17
    NCGC00023875-07
    NCGC00015500-03
    NCGC00015500-09
    1-(3-p-Fluorobenzoylpropyl)-4-p-chlorophenyl-4-hydroxypiperidine
    WLN: T6NTJ A3VR DF& DQ DR DG
    EINECS 200-155-6
    Pharmakon1600-01500325
    4763-EP2295061A1
    4763-EP2298776A1
    4763-EP2272972A1
    4763-EP2311803A1
    4763-EP2292614A1
    4763-EP2298731A1
    4'-Fluoro-4-(4-hydroxy-4-p-chlorophenylpiperidino)butyrophenone
    4763-EP2272537A2
    4763-EP2311801A1
    4763-EP2277876A1
    4763-EP2295439A1
    4763-EP2269990A1
    4763-EP2308870A2
    4763-EP2277872A1
    4763-EP2316834A1
    4763-EP2295413A1
    4763-EP2269989A1
    4763-EP2308867A2
    MolPort-000-883-311
    4763-EP2275420A1
    4763-EP2311837A1
    4763-EP2295412A1
    4763-EP2305260A1
    4763-EP2272973A1
    4763-EP2311824A1
    .gamma.-[4-(p-Chlorphenyl)-4-hydroxpiperidino]-p-fluorbutyrophenone
    4-[4-(para-Chlorophenyl)-4-hydroxypiperidino]-4'-fluorobutyrophenone
    4-(4-(para-Chlorophenyl)-4-hydroxypiperidino)-4'-fluorobutyrophenone
    4'-Fluoro-4-(4-(p-chlorophenyl)-4-hydroxypiperidinyl)butyrophenone
    4-[4-(p-Chlorophenyl)-4-hydroxypiperidino]-4'-fluorobutyrophenone
    4-(4-(p-Chlorophenyl)-4-hydroxypiperidino)-4'-fluorobutyrophenone
    4-[4-(4-Chlorophenyl)-4-hydroxypiperidino]-4'-fluorobutyrophenone
    5-21-02-00377 (Beilstein Handbook Reference)
    4-(4-Hydroxy-4'-chloro-4-phenylpiperidino)-4'-fluorobutyrophenone
    BRD-K67783091-001-04-8
    BRD-K67783091-001-05-5
    4'-Fluoro-4-(4-hydroxy-4-(4'-chlorophenyl)piperidino)butyrophenone
    4'-Fluoro-4-[4-hydroxy-4-(4'-chlorophenyl)piperidino]butyrophenone
    Butyrophenone, 4-(4-(p-chlorophenyl)-4-hydroxypiperidino)-4'-fluoro-
    Butyrophenone, 4-[4-(p-chlorophenyl)-4-hydroxypiperidino]-4'-fluoro-
    Butyrophenone, 4'-fluoro-4-(4-(p-chlorophenyl)-4-hydroxypiperidino)-
    4-[4-(4-chlorophenyl)-4-hydroxypiperidyl]-1-(4-fluorophenyl)butan-1-one
    4-[4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(4-fluorophenyl)-1-butanone
    4-(4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanone
    4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one
    4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidyl]-1-(4-fluorophenyl)-butan-1-one
    1-Butanone, 4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(4-fluorophenyl)-
    1-Butanone, 4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-
    4-[4-(4-Chlorophenyl)-4-hydroxy- 1-piperidinyl]-1-(4-fluorophenyl)- 1-butanone
    InChI=1/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2
    SmilesC1CN(CCC1(C2=CC=C(C=C2)Cl)O)CCCC(=O)C3=CC=C(C=C3)F
    3559 
     
    19534531, 12190308, 12873512, 12729675, n/a, 19072656, 22677319, 15324906, 16908150,
    FormulaC21H23ClFNO2
    Molweight375.864
    Heavy Atoms26
    Rotatable Bonds6
    H-bond donors1
    H-bond Acceptors 4
    Cluster numberNo cluster with more than 3 Compounds available
    Vendors
    ABBLIS Chemicals
    Abbott Labs
    ABI Chem
    AK Scientific, Inc. (AKSCI)
    AKos Consulting & Solutions
    Ambinter
    Calbiochem
    Chembase.cn
    ChemFrog
    ChemMol
    Hangzhou APIChem Technology
    HDH Pharma
    IS Chemical Technology
    MP Biomedicals
    Selleck Chemicals
    Sigma-Aldrich
    TCI (Tokyo Chemical Industry)
    Tetrahedron Scientific Inc
    TimTec


    Lidocaine Monohydrochloride



    Inhibition of:
    TREK: 180000 nM (ic50)
    Metabolism
    Extrarenal fraction (Q0)Elimination half-life (EHL)
    0.92h
    Synonymous names
    Lidocaine Monohydrochloride
    Lidocaine Hydrocarbonate
    Alphacaine;Xylocaine;lignocaine
    Xylocaine Endotracheal
    Cappicaine
    Lignocainum
    Lidocainum
    Lignocaine
    Xylestesin
    Dentipatch
    Lanabiotic
    Lidocaine Carbonate
    Alphacaine
    Xylesthesin
    Lingocaine
    Esracaine
    Isicaine
    Jetocaine
    Lidocaton
    Anestacon
    DermaFlex
    Maricaine
    Xilocaina
    Xylocaine
    Xylocitin
    Cuivasil
    Lidoderm
    Xylocard
    Remicaine
    Octocaine
    Xylocaine Viscous
    Dalcaine
    Dilocaine
    Leostesin
    Xylocain
    Isicaina
    lidocaine
    Gravocain
    Lidocaina
    Duncaine
    Versatis
    Xycaine
    Xilina
    Solcain
    Xllina
    Rucaina
    Xylocaine Dental Ointment
    Anestacon Jelly
    Xylotox
    EMBOLEX
    LIDOPEN
    Zingo
    Neosporin Plus
    Xylocaine-Mpf
    Lidamantle-HC
    Cito optadren
    Emla
    LQZ
    Lida-Mantle
    Rocephin Kit
    Norwood Sunburn Spray
    Emla Cream
    Xylocaine Test Dose
    Zilactin-L
    L-Caine
    After Burn Spray
    CHEMBL79
    AC1L1GGQ
    Xylocaine CO2
    Xylocaine-Mpf with Glucose
    ELA-Max
    After Burn Double Strength Spray
    alpha-Diethylamino-2,6-dimethylacetanilide
    After Burn Gel
    Xylocaine 5% Spinal
    Lidoject-2
    Lidoject-1
    Solarcaine aloe extra burn relief cream
    After Burn Double Strength Gel
    alfa-Dietilamino-2,6-dimetilacetanilide
    Xilocaina [Italian]
    Octocaine-50
    Diethylaminoaceto-2,6-xylidide
    AC1Q2Z7J
    Lidocaine (VAN)
    M620
    Dentipatch (TN)
    Octocaine-100
    Lidocaina [INN-Spanish]
    Xylocaine (TN)
    SureCN15689
    ARONIS23855
    Xyloneural (free base)
    Lidocainum [INN-Latin]
    CID3676
    C14H22N2O
    L0156
    S1357_Selleck
    CTK3J2126
    HMS548M19
    LS-805
    BIDD:GT0342
    L7757_SIGMA
    NSC40030
    L1026_SIGMA
    DB00281
    HMS2235O14
    HMS2051C21
    .alpha.-Diethylamino-2,6-dimethylacetanilide
    C07073
    HMS1989D21
    HMS1791D21
    nchembio.65-comp16
    CHEBI:6456
    A18187
    HMS3393C21
    HSDB 3350
    HMS2089E15
    .omega.-Diethylamino-2,6-dimethylacetanilide
    D00358
    Bio-0767
    DAP000121
    ST023341
    BBL005525
    Lidocaine [USAN:INN:JAN]
    SBB080556
    STK552033
    alfa-Dietilamino-2,6-dimetilacetanilide [Italian]
    Spectrum_001118
    KBioSS_000079
    AC-10282
    NSC 40030
    KBioGR_000599
    .alpha.-Diethylaminoaceto-2,6-xylidide
    Lopac-L-5647
    KBioGR_000079
    ANW-42187
    BSPBio_003004
    DSSTox_GSID_45166
    BSPBio_001359
    KBioSS_001598
    NSC-40030
    AB2000065
    BSPBio_000179
    Spectrum3_001392
    Maybridge1_002571
    SPBio_001525
    Spectrum2_001343
    Prestwick3_000050
    Lidocaine [USP:INN:BAN:JAN]
    Prestwick2_000050
    NINDS_000174
    Spectrum5_001549
    Prestwick1_000050
    DSSTox_RID_80716
    Spectrum4_000070
    Prestwick0_000050
    SPBio_002100
    DSSTox_CID_25166
    CCG-100824
    AB00053581
    Lidocaine (JP15/USP/INN)
    KBio2_002647
    Lopac0_000669
    KBio3_000158
    BPBio1_000197
    KBio2_001598
    KBio3_000157
    KBio2_000079
    KBio2_006734
    KBio1_000174
    I01-2704
    DivK1c_001323
    KBio2_005215
    AKOS001026768
    Lidocaine (JP16/USP/INN)
    2-Diethylamino-N-(2,6-dimethylphenyl)acetamide
    DivK1c_000174
    KBio2_004166
    KBio3_002224
    Bio1_001357
    Bio1_000868
    IDI1_033829
    BRN 2215784
    MLS001074177
    Bio1_000379
    MLS001423964
    IDI1_000174
    SMR000058189
    FT-0082378
    MLS000758263
    Bio2_000559
    CDS1_000283
    SAM001247018
    UNII-98PI200987
    MLS000069724
    Bio2_000079
    CPD000058189
    Tox21_110183
    137-58-6
    T0400-2927
    .alpha.-(Diethylamino)-2,6-acetoxylidide
    N-(2,6-dimethylphenyl)-N~2~,N~2~-diethylglycinamide
    CAS-73-78-9
    NCGC00015611-07
    NCGC00015611-13
    NCGC00015611-01
    NCGC00015611-14
    NCGC00015611-06
    NCGC00022176-09
    NCGC00015611-12
    NCGC00015611-10
    NCGC00015611-05
    NCGC00022176-08
    NCGC00015611-11
    NCGC00015611-04
    NCGC00022176-07
    NCGC00015611-09
    NCGC00015611-16
    NCGC00015611-03
    NCGC00022176-06
    NCGC00015611-08
    NCGC00015611-15
    NCGC00015611-02
    NCGC00022176-05
    EINECS 205-302-8
    CAS-137-58-6
    2-(Diethylamino)-N-(2,6-Dimethylphenyl)ethanamide
    2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide
    2-Diethylamino-N-(2,6-dimethyl-phenyl)-acetamide
    N1-(2,6-dimethylphenyl)-N2,N2-diethylglycinamide
    LIDOCAINE (73-58-6 (MONOHYDROCHLORIDE)
    73-78-9 (mono-hydrochloride)
    MolPort-001-783-478
    6108-05-0 (MONOHYDROCHLORIDE MONOHYDRATE))
    2-(Diethylamino)-N-(2,6-dimethylphenyl)-acetamide
    2', 2-(diethylamino)-
    WLN: 2N2 & 1VMR B1 F1
    2-(Diethylamino)-2',6'-acetoxylidide
    Acetamide, 2-(diethylamino)-N-(2,6-dimethylphenyl)-
    6108-05-0 (mono-hydrochloride, mono-hydrate)
    4-12-00-02538 (Beilstein Handbook Reference)
    N-(2,6-dimethylphenyl)-N(2),N(2)-diethylglycinamide
    2',6'-Acetoxylidide, 2-(diethylamino)-
    BRD-K52662033-001-02-6
    BRD-K52662033-003-05-5
    LIDOCAINE (73-58-6 (MONOHYDROCHLORIDE); 6108-05-0 (MONOHYDROCHLORIDE MONOHYDRATE))
    ''N''-(2,6-dimethylphenyl)-''N''2,''N''2-diethylglycinamide
    SmilesCCN(CC)CC(=O)NC1=C(C=CC=C1C)C
    3676 
     
    FormulaC14H22N2O
    Molweight234.337
    Heavy Atoms17
    Rotatable Bonds5
    H-bond donors1
    H-bond Acceptors 2
    Cluster numberNo cluster with more than 3 Compounds available
    Vendors
    ABBLIS Chemicals
    ABI Chem
    AK Scientific, Inc. (AKSCI)
    AKos Consulting & Solutions
    Alsachim
    Amadis Chemical
    Ambinter
    Anward
    Aronis
    Chembase.cn
    ChemExper Chemical Directory
    ChemFrog
    ChemMol
    Enamine
    FINETECH
    Hangzhou APIChem Technology
    IS Chemical Technology
    MP Biomedicals
    NIH Clinical Collection
    Selleck Chemicals
    Sigma-Aldrich
    TCI (Tokyo Chemical Industry)
    TimTec
    Vitas-M Laboratory


    Loxapinsuccinate



    Inhibition of:
    TREK: 19700 nM (ic50)
    Metabolism
    Extrarenal fraction (Q0)Elimination half-life (EHL)
     4 h
    Synonymous names
    Loxapinsuccinate
    Dibenzoazepine
    Dibenzacepin
    Loxitane Intramuscular
    Cloxazepine
    Lossapina
    Oxilapine
    Staccato loxapine
    Loxapinum
    Loxepine
    loxapine
    Loxapina
    Loxitane
    Loxapac
    Adasuve
    Loxapin
    Loxitane IM
    LOXITANE C
    Loxitane-C Oral Suspension
    AC1Q3ZWR
    CHEMBL831
    AC1L1H3Z
    Hydrofluoride 3170
    Lossapina [DCIT]
    Loxapina [INN-Spanish]
    CID3964
    SureCN94146
    C18H18ClN3O
    HF3170
    Adasuve (TN)
    Loxapinum [INN-Latin]
    DB00408
    AZ-004
    Loxapine (USAN/INN)
    S-805
    HSDB 3111
    S 805
    D02340
    C07104
    Loxapine [USAN:INN:BAN]
    LW 3170
    Loxapine [USAN:BAN:INN]
    HF 3170
    SUM 3170
    CS-1105
    SUM-3170
    DAP000311
    Spectrum_000355
    CHEBI:50841
    L001085
    SpecPlus_000823
    UNII-LER583670J
    BSPBio_003479
    LS-61562
    BSPBio_000204
    HY-17390
    KBioSS_000835
    CL-62362
    CL 62362
    Prestwick2_000132
    SPBio_002143
    Prestwick1_000132
    Spectrum5_001857
    SPBio_001814
    Prestwick0_000132
    Spectrum3_001830
    Spectrum2_001737
    Prestwick3_000132
    ZINC19796158
    CCG-204805
    PDSP2_001042
    KBio3_002983
    PDSP1_001058
    KBio2_005971
    DivK1c_006919
    BPBio1_000226
    Lopac0_000720
    KBio2_003403
    KBio2_000835
    KBio1_001863
    QTL1_000050
    CL 62,362
    CL-71,563
    BRN 0626753
    Loxapine|1977-10-2
    NCGC00021145-01
    NCGC00021145-03
    NCGC00021145-02
    NCGC00022279-05
    NCGC00021145-08
    NCGC00022279-04
    NCGC00021145-06
    NCGC00022279-03
    NCGC00021145-05
    1977-10-2
    NCGC00021145-07
    NCGC00021145-04
    EINECS 217-835-3
    MolPort-002-885-838
    27833-64-3 (succinate)
    54810-23-0 (mono-hydrochloride)
    2-Chloro-11-(4-methylpiperazino)dibenzo(b,f)(1,4)oxazepine
    BRD-K39915878-036-05-3
    BRD-K39915878-036-04-6
    8-chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzoxazepine
    8-chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,5]benzoxazepine
    2-Chloro-11-(4-methyl-1-piperazinyl)dibenz(b,f)(1,4)oxazepine
    2-chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]oxazepine
    2-Chloro-11-(4-methyl-1-piperazinyl)-dibenz(b,f)(1,4)oxazepine
    Dibenz[b,f][1,4]oxazepine, 2-chloro-11-(4-methyl-1-piperazinyl)-
    Dibenz(b,f)(1,4)oxazepine, 2-chloro-11-(4-methyl-1-piperazinyl)-
    SmilesCN1CCN(CC1)C2=NC3=CC=CC=C3OC4=C2C=C(C=C4)Cl
    3964 
     
    FormulaC18H18ClN3O
    Molweight327.808
    Heavy Atoms23
    Rotatable Bonds1
    H-bond donors0
    H-bond Acceptors 3
    Cluster numberNo cluster with more than 3 Compounds available
    Vendors
    ABI Chem
    Chembase.cn
    MedChemexpress MCE
    ZINC


    Quinidine Hydrochloride Monohydrate



    Inhibition of:
    TREK: 24100 nM (ic50)
    Synonymous names
    Quinidine hydrochloride monohydrate
    Quinicardine
    Novoquinidin
    Cardioquin
    Conchinine
    Conquinine
    Quiniduran
    Quinaglute
    chinidinum
    Quindine
    Pitayine
    Quinatime
    Conchinin
    Quinalan
    Coccinine
    Quinidex
    Chinidine
    Chinidin
    Auriquin
    Duraquin
    quinidina
    quinidine
    Quinidex Extentabs
    Quinidine sulfate
    Kinidin
    Pitayin
    Quinora
    Quinact
    Biquin durules
    Apo-Quinidine
    Quin-Release
    Quinaglute Dura-Tabs
    beta-Quinine
    AC1L9AHW
    Cin-Quin
    AC1Q4EZ6
    PubChem7994
    CHEMBL1294
    SureCN15944
    SureCN15943
    Q0006
    RH01857
    DB00908
    Q3625_SIGMA
    HMS2234L10
    bmse000511
    HMS3259O09
    22600_ALDRICH
    22600_FLUKA
    (+)-Quinidine
    CHEBI:28593
    AK-57138
    BSPBio_000160
    TCMDC-131239
    Prestwick3_000280
    (8R,9S)-Quinidine
    AB00514657
    BPBio1_000176
    AKOS015920101
    SMR000857275
    MLS001335914
    CPD000857275
    MLS001335913
    FT-0082277
    MLS002548869
    SAM002264644
    56-54-2
    50-54-4
    6151-39-9
    NCGC00091231-03
    NCGC00091231-02
    6151-40-2
    6591-63-5
    NCGC00091231-01
    SDCCGMLS-0066600.P001
    6-Methoxy-alpha-(5-vinyl-2-quinuclidinyl)-4-quinolinemethanol
    alpha-(6-Methoxy-4-quinolyl)-5-vinyl-2-quinuclidinemethanol
    6470-EP2272972A1
    6470-EP2314576A1
    6470-EP2272844A1
    6470-EP2305655A2
    6470-EP2272835A1
    6470-EP2277872A1
    6470-EP1441224A2
    6470-EP2275411A2
    6470-EP2272973A1
    6470-EP2314585A1
    (9S)-6'-Methoxycinchonan-9-ol
    AE-508/21131014
    BRD-K70799801-311-02-7
    (3'.alpha., 9S)-6'-Methoxycinchonan-9-ol
    (1S)-(6-Methoxyquinolin-4-yl)((2R,4S,5R)-5-vinylquinuclidin-2-yl)methanol
    (S)-[(2R,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl](6-methoxyquinolin-4-yl)methanol
    (S)-[(2R,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol
    (S)-[(4S,5R,7R)-5-ethenyl-1-azabicyclo[2.2.2]octan-7-yl]-(6-methoxyquinolin-4-yl)methanol
    (2-ethenyl- 4-azabicyclo [2.2.2] oct- 5-yl)- (6-methoxyquinolin- 4-yl)- methanol,
    SmilesCOC1=CC2=C(C=CN=C2C=C1)C(C3CC4CCN3CC4C=C)O
    441074 
     
    FormulaC20H24N2O2
    Molweight324.417
    Heavy Atoms24
    Rotatable Bonds4
    H-bond donors1
    H-bond Acceptors 4
    Cluster numberNo cluster with more than 3 Compounds available
    Vendors
    ABI Chem
    AK Scientific, Inc. (AKSCI)
    AKos Consulting & Solutions
    Ambinter
    Ark Pharm, Inc.
    CAPOT
    Chembase.cn
    ChemMol
    Chiralblock Biosciences
    FINETECH
    NIH Clinical Collection
    Oakwood Products
    R&D Chemicals
    Sigma-Aldrich
    TCI (Tokyo Chemical Industry)