Results for:
PubChem ID: 6212

Chloroform

Mass-Spectra

Compound Details

Synonymous names
Trichloormethaan
Trichloromethane
Methylidyne trichloride
Trichlormethan
trichlorocarbon
Triclorometano
CHLOROFORMWith Amylene
CHLOROFORMWith Ethanol
Trichloroform
CHLOROFORM
Chloroforme
Cloroformio
Methane trichloride
Methenyl trichloride
Chloroform, Spectrophotometric Grade
cloroform
Formyl trichloride
HEDRZPFGACZZDS-UHFFFAOYSA-N
Methenyl chloride
Methyl trichloride
trichloro-methane
chloroformium pro narcosi
Chloroform with amylene
Chloroform, analytical standard
Chloroform, Environmental Grade
tris(chloranyl)methane
WATER DISINFECTION BYPRODUCTS(CHLOROFORM)
chloro form
chloro-form
Chloroform-
CHCl3
trichloro- methane
CHLOROFORM, ACS
Chloroform, ethanol-free
Refrigerant R20
Trichloormethaan [Dutch]
Triclorometano [Italian]
Chloroform, HPLC Grade
Cloroformio [Italian]
methane trichloride
Trichlormethan [Czech]
AC1L1M1C
Chloroform, for HPLC
Chloroforme [French]
Methane, trichloro-
Chloroform (stabilized with ethanol)
Chloroform, pharmaceutical secondary standard; traceable to USP
WLN: GYGG
AC1Q3H37
Freon 20
GTPL2503
HSDB 56
KSC353S7H
8296AF
CHEMBL44618
UN1888
C0819
CCRIS 137
Chloroform - Reagent Grade ACS
Chloroform [NF XVII]
CTK2F3973
F 20
R 20
S0626
Y1314
Chloroform, purification grade, >=99%
NSC77361
RL04584
1,1,1-Trichloromethane
7V31YC746X
C13827
DSSTox_CID_306
LTBB002580
RCRA waste number U044
DTXSID1020306
IN018305
LS-1567
OR000433
OR257150
UN 1888
300037X
300040X
A835850
CHEBI:35255
L023971
NCI-C02686
UNII-7V31YC746X
ZINC8214524
AN-41895
DSSTox_GSID_20306
EyAE(1/4)xIe
NSC 77361
NSC-77361
Residual Solvent - Chloroform, pharmaceutical secondary standard; traceable to USP
SC-46857
Caswell No. 192
DSSTox_RID_75501
MFCD00000826
R 20 (Refrigerant)
AI3-24207
Chloroform, anhydrous, contains amylenes as stabilizer, >=99%
RTR-022720
TR-022720
AKOS000269026
EPA Pesticide Chemical Code 020701
RCRA waste no. U044
BRN 1731042
FT-0645128
67-66-3
Chloroform (stabilized with 2-Methyl-2-butene)
Chloroform, >=99%, PCR Reagent, contains amylenes as stabilizer
Tox21_111024
Tox21_202494
Chloroform, 99.8%, ACS Reagent
Chloroform, for HPLC, >=99.5%
Chloroform, for HPLC, >=99.8%
Chloroform, JIS special grade, >=99.0%
F0001-1775
I14-111606
CAS-67-66-3
Chloroform solution, 200 mug/mL in methanol, analytical standard
Chloroform, ACS spectrophotometric grade, >=99.8%, contains amylenes as stabilizer
8013-54-5
Chloroform, SAJ super special grade, >=99.0%
MCULE-5607930311
NCGC00090794-01
NCGC00090794-02
NCGC00260043-01
Chloroform [UN1888] [Poison]
Chloroform solution, certified reference material, 5000 mug/mL in methanol
EINECS 200-663-8
Chloroform, for HPLC, >=99.8%, amylene stabilized
Chloroform, technical, amylene stabilized, >=99% (GC)
Chloroform, ACS reagent, >=99.8%, contains amylenes as stabilizer
Chloroform, contains amylenes as stabilizer, ACS reagent, >=99.8%
Chloroform, contains ethanol as stabilizer, ACS reagent, >=99.8%
Residual Solvent Class 2 - Chloroform, United States Pharmacopeia (USP) Reference Standard
Chloroform, for residue analysis, suitable for 5000 per JIS
Chloroform, technical grade, 95%, contains 50 ppm Amylene
MolPort-000-871-941
Chloroform, p.a., 99.8%
Chloroform, ACS reagent, Reag. Ph. Eur., contains ethanol as stabilizer
Chloroform, LR, contains 100 ppm amylene as stabilizer, >=99%
InChI=1/CHCl3/c2-1(3)4/h1
Chloroform, UV HPLC spectroscopic, 99.9%, contains 50 ppm Amylene
Chloroform, AR, contains 1-2% ethanol as stabilizer, >=99.5%
Chloroform, AR, contains 100 ppm amylene as stabilizer, >=99.5%
4-01-00-00042 (Beilstein Handbook Reference)
Chloroform, anhydrous, >=99%, contains 0.5-1.0% ethanol as stabilizer
Chloroform, contains 100-200 ppm amylenes as stabilizer, >=99.5%
Chloroform, HPLC, 99.5% min., stabilized with ethanol 1L
Chloroform, suitable for 300 per JIS, >=99.0%, for residue analysis
Freon 20, R-20, UN 1888
BRD-K88785477-001-01-8
Chloroform, for HPLC, >=99.8% (chloroform + ethanol, GC)
Chloroform, ACS spectrophotometric grade, >=99.8%, contains 0.5-1.0% ethanol as stabilizer
Chloroform, UV HPLC spectroscopic, 99.0%, contains 0.6-1.0% Ethanol
Chloroform, HPLC Plus, for HPLC, GC, and residue analysis, >=99.9%, contains amylenes as stabilizer
Chloroform, ACS reagent, >=99.8%, contains 0.5-1.0% ethanol as stabilizer
Chloroform, SAJ first grade, >=99.0%, contains 0.4-0.8% ethanol
Chloroform solution, NIST standard reference material, 1% in acetone-d6 (99.9 atom % D)
Chloroform, for HPLC, >=99.8%, contains 0.5-1.0% ethanol as stabilizer
Chloroform solution, NMR reference standard, 1% in acetone-d6 (99.9 atom % D)
Chloroform solution, NMR reference standard, 3% in acetone-d6 (99.9 atom % D)
Chloroform, biotech. grade, >=99.8%, contains 0.5-1.0% ethanol as stabilizer
Chloroform, ReagentPlus(R), >=99.8%, contains 0.5-1.0% ethanol as stabilizer
Chloroform, contains ethanol as stabilizer, meets analytical specification of DAB9, BP, 99-99.4% (GC)
Chloroform, p.a., ACS reagent, 99.8%, contains 0.005% Amylene
Chloroform, puriss. p.a., ACS reagent, >=99.8% (chloroform + ethanol, GC)
Chloroform, p.a., ACS reagent, reag. ISO, 99.8%, contains 50 ppm Amylene
Chloroform, HPLC Plus, for HPLC, GC, and residue analysis, >=99.9%, contains 0.5-1.0% ethanol as stabilizer
Chloroform solution, NMR reference standard, 5% in acetone-d6 (99.9 atom % D), chromium(III) acetylacetonate 0.2 %
Chloroform solution, NMR reference standard, 50% in acetone-d6 (99.9 atom % D), chromium(III) acetylacetonate 0.2 %
Chloroform solution, NMR reference standard, 2% in chloroform-d (99.8 atom % D), NMR tube size 3 mm x 8 in.
Chloroform solution, NMR reference standard, 2% in chloroform-d (99.8 atom % D), NMR tube size 5 mm x 8 in.
Chloroform solution, NMR reference standard, 1% in acetone-d6 (99.9 atom % D), NMR tube size 3 mm x 8 in.
Chloroform solution, NMR reference standard, 1% in acetone-d6 (99.9 atom % D), NMR tube size 4 mm x 8 in.
Chloroform solution, NMR reference standard, 1% in acetone-d6 (99.9 atom % D), NMR tube size 8 mm x 8 in.
Chloroform solution, NMR reference standard, 2% in acetone-d6 (99.9 atom % D), NMR tube size 5 mm x 8 in.
Chloroform solution, NMR reference standard, 5% in acetone-d6 (99.9 atom % D), NMR tube size 3 mm x 8 in.
Chloroform solution, NMR reference standard, 5% in acetone-d6 (99.9 atom % D), NMR tube size 5 mm x 8 in.
Chloroform solution, NMR reference standard, 1% in acetone-d6 (99.9 atom % D), NMR tube size 10 mm x 8 in.
Chloroform solution, NMR reference standard, 10% in acetone-d6 (99.9 atom % D), NMR tube size 3 mm x 8 in.
Chloroform solution, NMR reference standard, 20% in acetone-d6 (99.9 atom % D), NMR tube size 5 mm x 8 in.
Chloroform solution, NMR reference standard, 0.3% in acetone-d6 (99.9 atom % D), NMR tube size 3 mm x 8 in.
Chloroform solution, NMR reference standard, 0.3% in acetone-d6 (99.9 atom % D), NMR tube size 5 mm x 8 in.
Chloroform, puriss. p.a., reag. ISO, reag. Ph. Eur., 99.0-99.4% (GC)
Chloroform solution, NMR reference standard, 1% in acetone-d6 (99,9 atom % D), TMS 0.1 %, NMR tube size 5 mm x 8 in.
Chloroform solution, NMR reference standard, 3% in acetone-d6 (99.9 atom % D), TMS 0.2 %, NMR tube size 3 mm x 8 in.
Chloroform solution, NMR reference standard, 3% in acetone-d6 (99.9 atom % D), TMS 0.2 %, NMR tube size 5 mm x 8 in.
Chloroform solution, NMR reference standard, 5% in acetone-d6 (99.9 atom % D), chromium(III) acetylacetonate 2 %, NMR tube size 10 mm x 8 in.
Chloroform solution, NMR reference standard, 50% in acetone-d6 (99.9 atom % D), chromium(III) acetylacetonate 0.2 %, NMR tube size 10 mm x 8 in.
Microorganism:

Yes

IUPAC namechloroform
SMILESC(Cl)(Cl)Cl
InchiInChI=1S/CHCl3/c2-1(3)4/h1H
FormulaCHCl3
PubChem ID6212
Molweight119.37
LogP1.83
Atoms5
Bonds4
H-bond Acceptor0
H-bond Donor0
Chemical Classificationhalogenated compounds

mVOC Specific Details

Volatilization
The Henry's Law constant for chloroform is 3.67X10-3 atm-cu m/mole(1). This Henry's Law constant indicates that chloroform is expected to volatilize from water surfaces(2). Based on this Henry's Law constant, the volatilization half-life from a model river (1 m deep, flowing 1 m/sec, wind velocity of 3 m/sec)(2) is estimated as 3.5 hours(SRC). The volatilization half-life from a model lake (1 m deep, flowing 0.05 m/sec, wind velocity of 0.5 m/sec)(2) is estimated as 4.4 days(SRC). Three laboratory studies of the evaporation of chloroform from water gave half-lives of 3-5.6 hrs with moderate mixing conditions(3-5). Chloroform volatilization constants were estimated in chilled (4 deg C) and boiled (100 deg C) water to be 0.88/hour and 1.50/hour, respectively(6). Estimated volatilization constants in experiments at 25 and 30 deg C ranged from 0.055/hour to 0.411/hour depending on the width and liquid level in the glass(6). Chloroform's Henry's Law constant indicates that volatilization from moist soil surfaces may occur(SRC). Chloroform is expected to volatilize from dry soil surfaces(SRC) based upon a vapor pressure of 197 mm Hg(7).
Literature: (1) Gossett JM; Environ Sci Tech 21: 202-6 (1987) (2) Lyman WJ et al; Handbook of Chemical Property Estimation Methods. Washington, DC: Amer Chem Soc pp. 15-1 to 15-29 (1990) (3) Smith JH et al; Environ Sci Technol 14: 190-6 (1980) (4) Rathbun RE, Tai DY; Water Res 15: 243-50 (1981) (5) Robert PV, Dandliker PG; Environ Sci Technol 17: 484-9 (1983) (6) Batterman S et al; Environ Sci Technol 34: 4418-24 (2000) (7) Boublik T et al; The Vapor Pressures of Pure Substances, Vol. 17; Amsterdam, Netherlands: Elsevier Sci (1984)
Soil Adsorption
A soil sorption study was conducted on chloroform in three distinctly different soils(1). Soils used were from Missouri (composed of 11.4% sand, 52.7% silt, 33.4% clay, 2.4% organic matter, at pH 6.9), California (composed of 45.1% sand, 35.2% silt, 21.7% clay, organic matter 1.7%, at pH 8.1), and Florida (composed of 91.7% sand, 6.3% silt, 2.0% clay, 1.6% organic matter, at pH 4.7)(1). The ratio of the amount of contaminant adsorbed in micrograms per gram of soil to the equilibrium concn in ppm was used to calculate a Kd value of 2.133 in the Missouri soil, 1.941 in the California soil, and 1.763 in the Florida soil(1). These values correspond to a Koc value ranging from 153-196 based upon the relationship between Kd and Koc(2). Chloroform is adsorbed most strongly to peat moss, less strongly to clay, very slightly to dolomite limestone and not at all to sand(3). The Koc values measured for 2 soils was 34; 3 other soils with the lowest organic carbon content in the same study gave no appreciable adsorption(4). Field experiments in which chloroform was injected into an aquifer and the concn in a series of observation wells determined, demonstrated that chloroform is very poorly retained by aquifer material (retardation factor 2-4), less so than other C1- and C2-halogenated compounds studied(4-5). Laboratory percolation studies with a sandy soil gave similar results (retardation factor <1.5)(6). Chloroform was reported to have a Koc of 65(7), 55(8), 47(9) and 34(10). According to a classification scheme(11), these Koc values suggest that chloroform is expected to have very high to moderate mobility in soil.
Literature: (1) Dural NH, Peng D; Hazard Ind Wastes 27: 528-37 (1995) (2) Lyman WJ et al; Handbook of Chemical Property Estimation Methods. Washington, DC: Amer Chem Soc pp. 4-2 (1990) (3) Dilling WL et al; Environ Sci Technol 9: 833-8 (1975) (4) Hutzler NJ et al; Amer Chem Soc 186th Mtg Div Environ Chem Preprint 23: 499-502 (1983) (5) Roberts PV et al; Water Res 16: 1025-35 (1982) (6) Wilson JT et al; J Environ Qual 10: 501-6 (1981) (7) Borisover MD, Graber ER; Chemosphere 34: 1761-76 (1997) (8) Harrison EM, Barker JF; J Contamin Hydrol 1: 349-73 (1987) (9) Chu W, Chan K-H; Sci Total Environ 248: 1-10 (2000) (10) Washington JW, Cameron BA; Environ Toxicol Chem 20: 1909-15 (2001) (11) Swann RL et al; Res Rev 85: 17-28 (1983)
Vapor Pressure
PressureReference
197 mm Hg at 25 deg CBoublik, T., Fried, V., and Hala, E., The Vapour Pressures of Pure Substances. Second Revised Edition. Amsterdam: Elsevier, 1984.
MS-Links
1D-NMR-Links

Microorganisms emitting the compound
KingdomSpeciesBiological FunctionOrigin/HabitatReference
BacteriaRalstonia SolanacearumnanaSpraker et al., 2014
FungiAspergillus FlavusnanaSpraker et al., 2014
Method
KingdomSpeciesGrowth MediumApplied MethodVerification
BacteriaRalstonia SolanacearumCasamino Acid Peptone Glucose agarSPME-GC/MSNo
FungiAspergillus Flavusglucose minimal mediumSPME-GC/MSNo